Glutathione peroxidase 4 (GPx-4), Rabbit Polyclonal Antibody

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Catalog Number
R-1589

    Product Info

  • Product Name Glutathione peroxidase 4 (GPx-4), Rabbit Polyclonal Antibody
  • Product Description google Rabbit anti-Glutathione peroxidase 4 (GPx-4) Polyclonal Antibody (Unconjugated), suitable for WB, IHC-Paraffin-embedded.
  • Alternative Names Phospholipid hydroperoxide glutathione peroxidase, mitochondrial; PHGPx;Glutathione peroxidase 4; GPx-4;GSHPx-4; GPX4;
  • Application(s) IHC-Paraffin-embedded, WB
  • Antibody Host Rabbit
  • Antibody Type Polyclonal
  • Specificity Human and rat mitochondrial glutathione peroxidase (GPx-4) Human; rat;
  • Species Reactivity Human, Rat
  • Immunogen Description A synthetic peptide (VNYTQLVDLHARYAEC) corresponding to the amino acids 78-93 of human glutathione peroxidase 4 (Isoform Mitochondrial) conjugated to KLH has been used as the immunogen. Human, rat and mouse sequences are identical.
  • Conjugate Unconjugated
  • Purity Description Whole serum
  • Regulatory Status For research use only.

    Specifications

  • Product Description Rabbit anti-Glutathione peroxidase 4 (GPx-4) Polyclonal Antibody (Unconjugated), suitable for WB, IHC-Paraffin-embedded.
  • Application(s) IHC-Paraffin-embedded, WB
  • Application Details WB, IHC. Typical working dilution for IHC is 1:200 to 1:1,000 depending on tissue and detection method. For WB, a dilution range of 1:1,000 to 1:2,000 is recommended. GPx-4 exists as a tetramer and can reform into multimeric complexes even under reduced conditions. The reported molecular weight of the GPx-4 monomer is 22 kDa but is reported to rapidly form oligomers, thus higher molecular weight bands greater than 22 kDa are expected. Mitochondrial preparations are also recommended to enhance signal. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
  • Target Glutathione peroxidase 4 (GPx-4)
  • Specificity Human and rat mitochondrial glutathione peroxidase (GPx-4) Human; rat;
  • Target Host Species Human
  • Species Reactivity Human, Rat
  • Antibody Host Rabbit
  • Antibody Type Polyclonal
  • Antibody Isotype Mixed
  • Conjugate Unconjugated
  • Immunogen Description A synthetic peptide (VNYTQLVDLHARYAEC) corresponding to the amino acids 78-93 of human glutathione peroxidase 4 (Isoform Mitochondrial) conjugated to KLH has been used as the immunogen. Human, rat and mouse sequences are identical.
  • Sequence VNYTQLVDLHARYAEC
  • Purity Description Whole serum
  • Format Lyophilized serum with 0.02% thimerosal
  • Reconstitution Instructions Spin vial briefly before opening. Reconstitute in 100 µL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material.
  • Storage Instructions At least 12 months after purchase at 2-8°C (lyophilized formulations). After reconstitution, aliquot and store at -20°C for a higher stability.Avoid freeze-thaw cycles.
  • Batch Number Please see item label.
  • Expiration Date 12 months after date of receipt (unopened vial).
  • Alternative Names Phospholipid hydroperoxide glutathione peroxidase, mitochondrial; PHGPx;Glutathione peroxidase 4; GPx-4;GSHPx-4; GPX4;
  • Uniprot Number P36969
  • Uniprot Number/Name P36969 (GPX4_HUMAN)
  • Scientific Background Glutathione peroxidase 4 (GPx-4) is involved in protecting cells against membrane lipid peroxidation and cell death.
  • Shipping Temperature 25°C (ambient)
  • UNSPSC CODE 41116161
  • Regulatory Status For research use only.

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