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Apoptosis-mediating surface antigen FAS (FAS), Rabbit Polyclonal Antibody
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Catalog Number
R-1018
- Product Name Apoptosis-mediating surface antigen FAS (FAS), Rabbit Polyclonal Antibody
- Product Description Rabbit anti-Apoptosis-mediating surface antigen FAS (FAS) Polyclonal Antibody (Unconjugated), suitable for WB, IHC-Frozen, IHC-Paraffin-embedded.
- Alternative Names FASLG receptor; Apo-1; CD95; Apt1; Tnfrsf6;
- Application(s) IHC-Frozen, IHC-Paraffin-embedded, WB
- Antibody Host Rabbit
- Antibody Type Polyclonal
- Specificity The specificity of this antibody has been confirmed by WB and IHC against the antigen. Rat; mouse;
- Species Reactivity Mouse, Rat
- Immunogen Description A synthetic peptide (YTDRKHYSDKCRRCAFCDEGHGL) corresponding to a region (87-109) from rat FAS. To enhance the immunological response, this peptide was coupled to carrier protein BSA.
- Conjugate Unconjugated
- Purity Description Affinity purified on antigen column
- Regulatory Status For research use only.
Product Info
- Product Description Rabbit anti-Apoptosis-mediating surface antigen FAS (FAS) Polyclonal Antibody (Unconjugated), suitable for WB, IHC-Frozen, IHC-Paraffin-embedded.
- Application(s) IHC-Frozen, IHC-Paraffin-embedded, WB
- Application Details Immunohistochemistry (IHC) and Western Blotting (WB). A concentration of 1.0 µg/mL is recommended for WB. Rat FAS has a predicted length of 324 residues and MW of 37 kDa. A concentration of 1.0-2.0 µg/mL is recommended to detect the protein in formalin fixed and paraffin embedded tissues as well as formalin/acetone fixed frozen tissues. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
- Target Apoptosis-mediating surface antigen FAS (FAS)
- Specificity The specificity of this antibody has been confirmed by WB and IHC against the antigen. Rat; mouse;
- Target Host Species Rat
- Species Reactivity Mouse, Rat
- Antibody Host Rabbit
- Antibody Type Polyclonal
- Antibody Isotype IgG
- Conjugate Unconjugated
- Immunogen Description A synthetic peptide (YTDRKHYSDKCRRCAFCDEGHGL) corresponding to a region (87-109) from rat FAS. To enhance the immunological response, this peptide was coupled to carrier protein BSA.
- Purity Description Affinity purified on antigen column
- Format Lyophilized with 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3
- Reconstitution Instructions Spin vial briefly before opening. Reconstitute in 100 µL sterile-filtered, ultrapure water to achieve an antibody concentration of 1 mg/mL. Centrifuge to remove any insoluble material.
- Storage Instructions At least 12 months after purchase at 2-8°C (lyophilized formulations). After reconstitution, aliquot and store at -20°C for a higher stability. Avoid freeze-thaw cycles
- Batch Number Please see item label.
- Expiration Date 12 months after date of receipt (unopened vial).
- Alternative Names FASLG receptor; Apo-1; CD95; Apt1; Tnfrsf6;
- Uniprot Number Q63199
- Uniprot Number/Name Q63199 (TNR6_RAT)
- Scientific Background FAS is a single-pass type I membrane protein and a member of the TNF-receptor superfamily. The interaction between this receptor and the FAS ligand (TNFSF6/FASLG) forms a death-inducing signalling complex that includes Fas-associated death domain protein (FADD), caspase 8 and caspase 10. Processing of the caspases in this complex leads to apoptosis.
- Shipping Temperature 25°C (ambient)
- UNSPSC CODE 41116161
- Regulatory Status For research use only.