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Apoptosis regulator BAX (BAX), Rabbit Polyclonal Antibody
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Catalog Number
R-1041
Discontinued
- Product Name Apoptosis regulator BAX (BAX), Rabbit Polyclonal Antibody
- Product Description Rabbit anti-Apoptosis regulator BAX (BAX) Polyclonal Antibody (Unconjugated), suitable for WB.
- Alternative Names Apoptosis regulator BAX; Bcl-2-like protein 4; BCL2L4; Bcl2-L-4;
- Application(s) WB
- Antibody Host Rabbit
- Antibody Type Polyclonal
- Specificity The specificity of this antibody has been confirmed by WB against the antigen. Human; mouse; rat;
- Species Reactivity Human, Mouse, Rat
- Immunogen Description A synthetic peptide (DELDSNMELQRMIA) corresponding to a region (68-81) from human Bax isoform alpha. To enhance the immunological response, this peptide was coupled to carrier protein BSA.
- Conjugate Unconjugated
- Purity Description Affinity purified on antigen column
- Regulatory Status For research use only.
Product Info
- Product Description Rabbit anti-Apoptosis regulator BAX (BAX) Polyclonal Antibody (Unconjugated), suitable for WB.
- Application(s) WB
- Application Details Western Blotting (WB). A concentration of 1.0-2.0 µg/mL is recommended for WB. Human Bax (isoform alpha) has a predicted length of 192 amino acids and MW of 21 kDa. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
- Target Apoptosis regulator BAX (BAX)
- Specificity The specificity of this antibody has been confirmed by WB against the antigen. Human; mouse; rat;
- Target Host Species Human
- Species Reactivity Human, Mouse, Rat
- Antibody Host Rabbit
- Antibody Type Polyclonal
- Antibody Isotype IgG
- Conjugate Unconjugated
- Immunogen Description A synthetic peptide (DELDSNMELQRMIA) corresponding to a region (68-81) from human Bax isoform alpha. To enhance the immunological response, this peptide was coupled to carrier protein BSA.
- Purity Description Affinity purified on antigen column
- Format Lyophilized with 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3
- Reconstitution Instructions Spin vial briefly before opening. Reconstitute in 100 µL sterile-filtered, ultrapure water to achieve an antibody concentration of 1 mg/mL. Centrifuge to remove any insoluble material.
- Storage Instructions At least 12 months after purchase at 2-8°C (lyophilized formulations). After reconstitution, aliquot and store at -20°C for a higher stability. Avoid freeze-thaw cycles
- Batch Number Please see item label.
- Expiration Date 12 months after date of receipt (unopened vial).
- Alternative Names Apoptosis regulator BAX; Bcl-2-like protein 4; BCL2L4; Bcl2-L-4;
- Uniprot Number Q07812
- Uniprot Number/Name Q07812 (BAX_HUMAN)
- Scientific Background Bax is a member of the Bcl-2 family of proteins which act as anti- or pro-apoptotic regulators. Bax forms a heterodimer with Bcl-2 and functions as an apoptotic activator by accelerating programmed cell death. Bax expression is regulated by the tumor suppressor p53 and has been shown to be involved in p53-mediated apoptosis. A number of Bax isoforms are produced from alternative splicing.
- Shipping Temperature 25°C (ambient)
- UNSPSC CODE 41116161
- Regulatory Status For research use only.
Specifications
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Specific References
Wei H et al. (2021) PCDH8 protects MPP+-induced neuronal injury in SH-SY5Y cells by inhibiting MAPK pathway. Mol Cell Toxicol. [Epub ahead of print] Application: WB. Species: Human.
Yin F et al. (2021) Pyrroline-5-Carboxylate Reductase-2 Promotes Colorectal Cancer Progression via Activating PI3K/AKT/mTOR Pathway. Dis Markers. Article ID 9950663. Application: WB. Species: Human.