Beclin-1, Rabbit Polyclonal Antibody

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Catalog Number
R-141

    Product Info

  • Product Name Beclin-1, Rabbit Polyclonal Antibody
  • Product Description google Rabbit anti-Beclin-1 Polyclonal Antibody (Unconjugated), suitable for IHC-Frozen.
  • Alternative Names Coiled-coil myosin-like BCL2-interacting protein; Protein GT197; APG 6; BECN1;
  • Application(s) IHC-Frozen
  • Antibody Host Rabbit
  • Antibody Type Polyclonal
  • Specificity Specific for Beclin-1. Human, other species have not yet been tested.
  • Species Reactivity Human
  • Immunogen Description C-terminal of human Beclin-1 conjugated to Blue Carrier Protein.
  • Conjugate Unconjugated
  • Purity Description Whole serum
  • Regulatory Status For research use only.

    Specifications

  • Product Description Rabbit anti-Beclin-1 Polyclonal Antibody (Unconjugated), suitable for IHC-Frozen.
  • Application(s) IHC-Frozen
  • Application Details IHC. A dilution of 1:100 to 1:2000 dilution is recommended for these applications. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
  • Target Beclin-1
  • Specificity Specific for Beclin-1. Human, other species have not yet been tested.
  • Target Host Species Human
  • Species Reactivity Human
  • Antibody Host Rabbit
  • Antibody Type Polyclonal
  • Antibody Isotype Mixed
  • Conjugate Unconjugated
  • Immunogen Description C-terminal of human Beclin-1 conjugated to Blue Carrier Protein.
  • Purity Description Whole serum
  • Format Lyophilized
  • Reconstitution Instructions Spin vial briefly before opening. Reconstitute in 100 µL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material.
  • Storage Instructions After reconstitution keep aliquots at -20°C for a higher stability, and at 2-8°C with an appropriate antibacterial agent. Avoid repetitive freeze/thaw cycles.
  • Batch Number Please see item label.
  • Expiration Date 12 months after date of receipt (unopened vial).
  • Alternative Names Coiled-coil myosin-like BCL2-interacting protein; Protein GT197; APG 6; BECN1;
  • Uniprot Number Q14457
  • Uniprot Number/Name Q14457 (BECN1_HUMAN)
  • Scientific Background Beclin-1 plays a central role in autophagy. It may also play a role in antiviral host defense. It is ubiquitously expressed and it localises to the cytoplasm, golgi apparatus membrane, and in dendrites and cell bodies of cerbellar Purkinje cells. The unprocessed precursor has a length of 450 amino acids and an estimated molecular weight of 51.89 kDa.
  • Shipping Temperature 25°C (ambient)
  • UNSPSC CODE 41116161
  • Regulatory Status For research use only.

    Images, Protocols & SDS

  • Confocal microscopy on immunofluorescently detected Beclin-1 in cytospin-isolated human white blood cells using Rabbit antibody to Beclin-1: whole serum (R-141-100) at a dilution of 1: 200, incubated for 1 h at room temperature. The cells were double-stained for Beclin 1 appearing in red and Myeloperoxidase appearing in green. The cells were counter stained with Hoechst Dye (blue colour). Here, the merged picture is presented.

    Citations & References