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Rho-associated protein kinase 2, Rabbit Polyclonal Antibody
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Catalog Number
R-1612
Discontinued
- Product Name Rho-associated protein kinase 2, Rabbit Polyclonal Antibody
- Product Description Rabbit anti-Rho-associated protein kinase 2 Polyclonal Antibody (Unconjugated), suitable for WB, IHC-Frozen, IHC-Paraffin-embedded.
- Alternative Names EC 2.7.11.1; Rho-associated; coiled-coil-containing protein kinase 2; p164 ROCK-2; Rho kinase 2; ROCK2; KIAA0619;
- Application(s) IHC-Frozen, IHC-Paraffin-embedded, WB
- Antibody Host Rabbit
- Antibody Type Polyclonal
- Specificity Human (WB, IHC); rat (WB); predicted to react with mouse due to sequence homology;
- Species Reactivity Human, Mouse (Predicted), Rat
- Immunogen Description A synthetic peptide corresponding to a region (35-51) from human Rho-associated protein kinase 2.
- Conjugate Unconjugated
- Purity Description Affinity purified on antigen column
- Regulatory Status For research use only.
Product Info
- Product Description Rabbit anti-Rho-associated protein kinase 2 Polyclonal Antibody (Unconjugated), suitable for WB, IHC-Frozen, IHC-Paraffin-embedded.
- Application(s) IHC-Frozen, IHC-Paraffin-embedded, WB
- Application Details Immunohistochemistry (IHC) and Western Blotting (WB). A concentration of 0.1-0.5 µg/mL is recommended for WB. Human Rho-associated protein kinase 2 has a predicted length of 1388 amino acids and MW of 160 kDa. A concentration of 0.5-1.0 µg/mL is recommended to detect the protein in formalin fixed and paraffin embedded tissues. Heat mediated antigen retrieval is required. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
- Target Rho-associated protein kinase 2
- Specificity Human (WB, IHC); rat (WB); predicted to react with mouse due to sequence homology;
- Target Host Species Human
- Species Reactivity Human, Mouse (Predicted), Rat
- Antibody Host Rabbit
- Antibody Type Polyclonal
- Antibody Isotype IgG
- Conjugate Unconjugated
- Immunogen Description A synthetic peptide corresponding to a region (35-51) from human Rho-associated protein kinase 2.
- Purity Description Affinity purified on antigen column
- Format Lyophilized with 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3
- Reconstitution Instructions Spin vial briefly before opening. Reconstitute in 100 µL sterile-filtered, ultrapure water to achieve an antibody concentration of 1 mg/mL. Centrifuge to remove any insoluble material.
- Storage Instructions At least 12 months after purchase at 2-8°C (lyophilized formulations). After reconstitution, aliquot and store at -20°C for a higher stability. Avoid freeze-thaw cycles.
- Batch Number Please see item label.
- Expiration Date 12 months after date of receipt (unopened vial).
- Alternative Names EC 2.7.11.1; Rho-associated; coiled-coil-containing protein kinase 2; p164 ROCK-2; Rho kinase 2; ROCK2; KIAA0619;
- Uniprot Number O75116
- Uniprot Number/Name O75116 (ROCK2_HUMAN)
- Scientific Background Rho-associated protein kinase 2 (ROCK2) is a serine/threonine kinase that phosphorylates many important signalling proteins involved in the regulation of cytokinesis, smooth muscle contraction, the formation of actin stress fibers and focal adhesions complexes as well as malignant cell transformation, tumor invasion and metastasis.
- Shipping Temperature 25°C (ambient)
- UNSPSC CODE 41116161
- Regulatory Status For research use only.