1800 605-5127
+61 (0)8 8352 7711
Checkpoint homolog CHK2, Rabbit Polyclonal Antibody
As low as
US$427.00
Only %1 left
Catalog Number
R-1111
- Product Name Checkpoint homolog CHK2, Rabbit Polyclonal Antibody
- Product Description Rabbit anti-Checkpoint homolog CHK2 Polyclonal Antibody (Unconjugated), suitable for WB.
- Alternative Names Serine/threonine-protein kinase Chk2; EC 2.7.11.1; Cds1; CHEK2; CHK2; RAD53;
- Application(s) WB
- Antibody Host Rabbit
- Antibody Type Polyclonal
- Specificity The specificity of this antibody has been confirmed by WB against the antigen. Human; rat; predicted to react with mouse due to sequence homology;
- Species Reactivity Human, Mouse (Predicted), Rat
- Immunogen Description A synthetic peptide (FSEHRTQVSLKDQIT) corresponding to a region (427-441) from human Checkpoint homolog CHK2. To enhance the immunological response, this peptide was coupled to carrier protein BSA.
- Conjugate Unconjugated
- Purity Description Affinity purified on antigen column
- Regulatory Status For research use only.
Product Info
- Product Description Rabbit anti-Checkpoint homolog CHK2 Polyclonal Antibody (Unconjugated), suitable for WB.
- Application(s) WB
- Application Details Western Blotting (WB). A concentration of 0.75 µg/mL is recommended for WB. Human Checkpoint homolog CHK2 (isoform 1) has a predicted length of 543 residues and MW of 61 kDa. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
- Target Checkpoint homolog CHK2
- Specificity The specificity of this antibody has been confirmed by WB against the antigen. Human; rat; predicted to react with mouse due to sequence homology;
- Target Host Species Human
- Species Reactivity Human, Mouse (Predicted), Rat
- Antibody Host Rabbit
- Antibody Type Polyclonal
- Antibody Isotype IgG
- Conjugate Unconjugated
- Immunogen Description A synthetic peptide (FSEHRTQVSLKDQIT) corresponding to a region (427-441) from human Checkpoint homolog CHK2. To enhance the immunological response, this peptide was coupled to carrier protein BSA.
- Purity Description Affinity purified on antigen column
- Format Lyophilized with 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3
- Reconstitution Instructions Spin vial briefly before opening. Reconstitute in 100 µL sterile-filtered, ultrapure water to achieve an antibody concentration of 1 mg/mL. Centrifuge to remove any insoluble material.
- Storage Instructions At least 12 months after purchase at 2-8°C (lyophilized formulations). After reconstitution, aliquot and store at -20°C for a higher stability.Avoid freeze-thaw cycles.
- Batch Number Please see item label.
- Expiration Date 12 months after date of receipt (unopened vial).
- Alternative Names Serine/threonine-protein kinase Chk2; EC 2.7.11.1; Cds1; CHEK2; CHK2; RAD53;
- Uniprot Number O96017
- Uniprot Number/Name O96017 (CHK2_HUMAN)
- Scientific Background Checkpoint homolog CHK2 is an important cell cycle checkpoint regulator. The protein is rapidly activated by phosphorylation in response to DNA damage and to replication block. When activated, CHK2 is known to prevent entry into mitosis and has been shown to regulate the tumor suppressor protein p53, leading to cell cycle arrest in G1. At least 12 isoforms are produced by alternative splicing.
- Shipping Temperature 25°C (ambient)
- UNSPSC CODE 41116161
- Regulatory Status For research use only.