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Presenilin-2 (PS-2), Rabbit Polyclonal Antibody
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Catalog Number
R-1479
- Product Name Presenilin-2 (PS-2), Rabbit Polyclonal Antibody
- Product Description Rabbit anti-Presenilin-2 (PS-2) Polyclonal Antibody (Unconjugated), suitable for WB, IHC-Frozen, IHC-Paraffin-embedded.
- Alternative Names PS-2; AD3LP; AD5; E5-1; STM-2; PSEN2; AD4; PS2; PSNL2; STM2;
- Application(s) IHC-Frozen, IHC-Paraffin-embedded, WB
- Antibody Host Rabbit
- Antibody Type Polyclonal
- Specificity The specificity of this antibody has been confirmed by WB (Human, Rat) and IHC (Rat) against the antigen. Human; rat; predicted to react with mouse due to sequence homology
- Species Reactivity Human, Mouse (Predicted), Rat
- Immunogen Description A synthetic peptide corresponding to a region (319-334 aa) from human Presenilin-2.
- Conjugate Unconjugated
- Purity Description Affinity purified
- Regulatory Status For research use only.
Product Info
- Product Description Rabbit anti-Presenilin-2 (PS-2) Polyclonal Antibody (Unconjugated), suitable for WB, IHC-Frozen, IHC-Paraffin-embedded.
- Application(s) IHC-Frozen, IHC-Paraffin-embedded, WB
- Application Details Western Blotting (WB) and Immunohistochemistry (IHC). A concentration of 1.0 µg/mL is recommended for WB. Human Presenilin-2 (isoform 1) has a predicted length of 448 amino acids and MW of 50 kDa. A concentration of 1.0 µg/mL is recommended for IHC to detect the protein in formalin fixed and paraffin embedded tissues. Heat mediated antigen retrieval is required. A concentration of 1.0 µg/mL is also recommended for IHC in frozen tissue. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
- Target Presenilin-2 (PS-2)
- Specificity The specificity of this antibody has been confirmed by WB (Human, Rat) and IHC (Rat) against the antigen. Human; rat; predicted to react with mouse due to sequence homology
- Target Host Species Human
- Species Reactivity Human, Mouse (Predicted), Rat
- Antibody Host Rabbit
- Antibody Type Polyclonal
- Antibody Isotype IgG
- Conjugate Unconjugated
- Immunogen Description A synthetic peptide corresponding to a region (319-334 aa) from human Presenilin-2.
- Purity Description Affinity purified
- Format Lyophilized with 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3
- Reconstitution Instructions Spin vial briefly before opening. Reconstitute in 100 µL sterile-filtered, ultrapure water to achieve an antibody concentration of 1 mg/mL. Centrifuge to remove any insoluble material.
- Storage Instructions At least 12 months after purchase at 2-8°C (lyophilized formulations). After reconstitution, aliquot and store at -20°C for a higher stability. Avoid freeze-thaw cycles.
- Batch Number Please see item label.
- Expiration Date 12 months after date of receipt (unopened vial).
- Alternative Names PS-2; AD3LP; AD5; E5-1; STM-2; PSEN2; AD4; PS2; PSNL2; STM2;
- Uniprot Number P49810
- Uniprot Number/Name P49810 (PSN2_HUMAN)
- Scientific Background Presenilin-2 is a multi-pass membrane protein and component of the gamma-secretase complex. At least 2 isoforms are produced by alternative splicing.
- Shipping Temperature 25°C (ambient)
- UNSPSC CODE 41116161
- Regulatory Status For research use only.