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Tumor necrosis factor receptor 1 (TNFR1), Rabbit Polyclonal Antibody
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Catalog Number
R-1127
- Product Name Tumor necrosis factor receptor 1 (TNFR1), Rabbit Polyclonal Antibody
- Product Description Rabbit anti-Tumor necrosis factor receptor 1 (TNFR1) Polyclonal Antibody (Unconjugated), suitable for WB, IHC-Frozen, IHC-Paraffin-embedded.
- Alternative Names p60; TNF-R1; TNF-RI; TNFR-I; p55; CD120a; TNFRSF1A; TNFAR; TNFR1;
- Application(s) IHC-Frozen, IHC-Paraffin-embedded, WB
- Antibody Host Rabbit
- Antibody Type Polyclonal
- Specificity The specificity of this antibody has been confirmed by WB and IHC against the antigen. Human;
- Species Reactivity Human
- Immunogen Description A synthetic peptide corresponding to a region (195-211) from human Tumor necrosis factor receptor 1 (precursor). To enhance the immunological response, this peptide was coupled to carrier protein BSA.
- Conjugate Unconjugated
- Purity Description Affinity purified on antigen column
- Regulatory Status For research use only.
Product Info
- Product Description Rabbit anti-Tumor necrosis factor receptor 1 (TNFR1) Polyclonal Antibody (Unconjugated), suitable for WB, IHC-Frozen, IHC-Paraffin-embedded.
- Application(s) IHC-Frozen, IHC-Paraffin-embedded, WB
- Application Details Immunohistochemistry (IHC) and Western Blotting (WB). A concentration of 1.0 µg/mL is recommended for WB. Human TNF Receptor 1 (precursor) has a predicted length of 455 residues and MW of 51 kDa. A concentration of 1.0 µg/mL is recommended to detect the protein in formalin fixed and paraffin embedded tissues. Heat mediated antigen retrieval is required. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
- Target Tumor necrosis factor receptor 1 (TNFR1)
- Specificity The specificity of this antibody has been confirmed by WB and IHC against the antigen. Human;
- Target Host Species Human
- Species Reactivity Human
- Antibody Host Rabbit
- Antibody Type Polyclonal
- Antibody Isotype IgG
- Conjugate Unconjugated
- Immunogen Description A synthetic peptide corresponding to a region (195-211) from human Tumor necrosis factor receptor 1 (precursor). To enhance the immunological response, this peptide was coupled to carrier protein BSA.
- Purity Description Affinity purified on antigen column
- Format Lyophilized with 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3
- Reconstitution Instructions Spin vial briefly before opening. Reconstitute in 100 µL sterile-filtered, ultrapure water to achieve an antibody concentration of 1 mg/mL. Centrifuge to remove any insoluble material.
- Storage Instructions At least 12 months after purchase at 2-8°C (lyophilized formulations). After reconstitution, aliquot and store at -20°C for a higher stability. Avoid freeze-thaw cycles
- Batch Number Please see item label.
- Expiration Date 12 months after date of receipt (unopened vial).
- Alternative Names p60; TNF-R1; TNF-RI; TNFR-I; p55; CD120a; TNFRSF1A; TNFAR; TNFR1;
- Uniprot Number P19438
- Uniprot Number/Name P19438 (TNR1A_HUMAN)
- Scientific Background Tumor necrosis factor receptor 1 (TNF Receptor 1) binds cytokines TNF-alpha and TNF-beta resulting in the activation of pathways involved in both cell survival and apoptosis. TNF Receptor 1 contains an extracellular death domain that binds to the death domain adaptor protein TRADD and triggers the activation of caspases. At least 3 isoforms are produced by alternative splicing.
- Shipping Temperature 25°C (ambient)
- UNSPSC CODE 41116161
- Regulatory Status For research use only.