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Cyclin-dependent kinase 7 (CDK7), Mouse Monoclonal Antibody
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Catalog Number
M-1175
- Product Name Cyclin-dependent kinase 7 (CDK7), Mouse Monoclonal Antibody
- Product Description Mouse anti-Cyclin-dependent kinase 7 (CDK7) Monoclonal Antibody (Unconjugated), suitable for WB, IHC-Frozen, IHC-Paraffin-embedded.
- Alternative Names Cell division protein kinase 7; CDK-activating kinase; CAK; CAK1; TFIIH basal transcription factor complex kinase subunit; 39 kDa protein kinase; P39 Mo15; STK1; CDK7; MO15; CDKN7; Serine threonine kinase Stk1;
- Application(s) IHC-Frozen, IHC-Paraffin-embedded, WB
- Antibody Host Mouse
- Antibody Type Monoclonal
- Specificity The specificity of this antibody has been confirmed by WB and IHC against the antigen. Human;
- Species Reactivity Human
- Immunogen Description Recombinant human Cyclin-dependent kinase 7 (CDK7)
- Conjugate Unconjugated
- Purity Description IgG
- Regulatory Status For research use only.
Product Info
- Product Description Mouse anti-Cyclin-dependent kinase 7 (CDK7) Monoclonal Antibody (Unconjugated), suitable for WB, IHC-Frozen, IHC-Paraffin-embedded.
- Application(s) IHC-Frozen, IHC-Paraffin-embedded, WB
- Application Details Immunohistochemistry (IHC) and Western Blotting (WB). A concentration of 0.25 μg/mL is recommended for WB. Human CDK7 has a predicted length of 346 residues and MW of 39 kDa. A concentration of 0.5 µg/mL is recommended to detect the protein in formalin/acetone fixed frozen tissues. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
- Target Cyclin-dependent kinase 7 (CDK7)
- Specificity The specificity of this antibody has been confirmed by WB and IHC against the antigen. Human;
- Target Host Species Human
- Species Reactivity Human
- Antibody Host Mouse
- Antibody Type Monoclonal
- Antibody Isotype IgG
- Clone Name IMD-26
- Conjugate Unconjugated
- Immunogen Description Recombinant human Cyclin-dependent kinase 7 (CDK7)
- Purity Description IgG
- Format Lyophilized from 1.2% sodium acetate, 2 mg BSA, 0.01 mg NaN3
- Reconstitution Instructions Spin vial briefly before opening. Reconstitute in 1 mL of sterile-filtered PBS (pH 7.4) to achieve an antibody concentration of 100 µg/mL. Centrifuge to remove any insoluble material.
- Storage Instructions At least 12 months after purchase at 2-8°C (lyophilized formulations). After reconstitution, aliquot and store at -20°C for a higher stability.Avoid freeze-thaw cycles
- Batch Number Please see item label.
- Expiration Date 12 months after date of receipt (unopened vial).
- Alternative Names Cell division protein kinase 7; CDK-activating kinase; CAK; CAK1; TFIIH basal transcription factor complex kinase subunit; 39 kDa protein kinase; P39 Mo15; STK1; CDK7; MO15; CDKN7; Serine threonine kinase Stk1;
- Uniprot Number P50613
- Uniprot Number/Name P50613 (CDK7_HUMAN)
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Scientific Background
Cyclin-dependent kinase 7 (CDK7) belongs to the cyclin-dependent protein kinase family. CDK7 associates with cyclin H and MAT1 to form the trimeric CDK-activating kinase (CAK) complex. CAK activates cyclin-associated kinases such as CDK4 and CDK6 by threonine phosphorylation.
- Shipping Temperature 25°C (ambient)
- UNSPSC CODE 41116161
- Regulatory Status For research use only.