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T-cell surface glycoprotein CD8 alpha chain, Mouse Monoclonal Antibody
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Catalog Number
M-1166
- Product Name T-cell surface glycoprotein CD8 alpha chain, Mouse Monoclonal Antibody
- Product Description Mouse anti-T-cell surface glycoprotein CD8 alpha chain Monoclonal Antibody (Unconjugated), suitable for IHC-Frozen, IHC-Paraffin-embedded.
- Alternative Names T-cell surface glycoprotein CD8 alpha chain; T-lymphocyte differentiation antigen T8/Leu-2; CD8a; MAL; T-cell surface glycoprotein CD8 beta chain; CD8b; CD8B; CD8B1;
- Application(s) IHC-Frozen, IHC-Paraffin-embedded
- Antibody Host Mouse
- Antibody Type Monoclonal
- Specificity The specificity of this antibody has been confirmed by immunohistochemistry against the antigen. Human; rat;
- Species Reactivity Human, Rat
- Immunogen Description Human thymocytes followed by peripheral blood T-cells
- Conjugate Unconjugated
- Purity Description IgG
- Regulatory Status For research use only.
Product Info
- Product Description Mouse anti-T-cell surface glycoprotein CD8 alpha chain Monoclonal Antibody (Unconjugated), suitable for IHC-Frozen, IHC-Paraffin-embedded.
- Application(s) IHC-Frozen, IHC-Paraffin-embedded
- Application Details Immunohistochemistry (IHC-Frozen). A concentration of 1.0 µg/mL is recommended to detect CD8 in formalin/acetone fixed tissues. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
- Target T-cell surface glycoprotein CD8 alpha chain
- Specificity The specificity of this antibody has been confirmed by immunohistochemistry against the antigen. Human; rat;
- Target Host Species Human
- Species Reactivity Human, Rat
- Antibody Host Mouse
- Antibody Type Monoclonal
- Antibody Isotype IgG
- Clone Name CA-8
- Conjugate Unconjugated
- Immunogen Description Human thymocytes followed by peripheral blood T-cells
- Purity Description IgG
- Format Lyophilized from 1.2% sodium acetate, 2 mg BSA, 0.01 mg NaN3
- Reconstitution Instructions Spin vial briefly before opening. Reconstitute in 1 mL of sterile-filtered PBS (pH 7.4) to achieve an antibody concentration of 100 µg/mL. Centrifuge to remove any insoluble material.
- Storage Instructions At least 12 months after purchase at 2-8°C (lyophilized formulations). After reconstitution, aliquot and store at -20°C for a higher stability. Avoid freeze-thaw cycles.
- Batch Number Please see item label.
- Expiration Date 12 months after date of receipt (unopened vial).
- Alternative Names T-cell surface glycoprotein CD8 alpha chain; T-lymphocyte differentiation antigen T8/Leu-2; CD8a; MAL; T-cell surface glycoprotein CD8 beta chain; CD8b; CD8B; CD8B1;
- Uniprot Number P01732
- Uniprot Number/Name P01732 (CD8A_HUMAN)
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Scientific Background
CD8 is a cell surface glycoprotein found on most cytotoxic T lymphocytes. The antigen is either a homodimer composed of two alpha chains or a disulphide-linked heterodimer composed of one alpha and one beta chain.
At least 2 isoforms of the CD8 alpha chain and 6 isoforms of the beta chain are produced by alternative splicing.
- Shipping Temperature 25°C (ambient)
- UNSPSC CODE 41116161
- Regulatory Status For research use only.