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Protein jagged-1 (JAG1), Mouse Monoclonal Antibody
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US$417.00
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Catalog Number
M-800
- Product Name Protein jagged-1 (JAG1), Mouse Monoclonal Antibody
- Product Description Mouse anti-Protein jagged-1 (JAG1) Monoclonal Antibody (Unconjugated), suitable for WB, ELISA.
- Alternative Names Protein jagged-1; Jagged 1; hJ1; CD339 antigen; JAG1; JAGL1;
- Application(s) ELISA, WB
- Antibody Host Mouse
- Antibody Type Monoclonal
- Specificity Specificity was demonstrated by WB against the antigen. Human. Other species not yet tested.
- Species Reactivity Human
- Immunogen Description Partial recombinant human JAG1 (amino acids 531-621) with a GST tag
- Conjugate Unconjugated
- Purity Description Ascites fluid
- Regulatory Status For research use only.
Product Info
- Product Description Mouse anti-Protein jagged-1 (JAG1) Monoclonal Antibody (Unconjugated), suitable for WB, ELISA.
- Application(s) ELISA, WB
- Application Details This antibody is recommended for direct ELISA and WB. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
- Target Protein jagged-1 (JAG1)
- Specificity Specificity was demonstrated by WB against the antigen. Human. Other species not yet tested.
- Target Host Species Human
- Species Reactivity Human
- Antibody Host Mouse
- Antibody Type Monoclonal
- Antibody Isotype IgG
- Clone Name 1E12
- Conjugate Unconjugated
- Immunogen Description Partial recombinant human JAG1 (amino acids 531-621) with a GST tag
- Purity Description Ascites fluid
- Format Lyophilized
- Reconstitution Instructions Spin vial briefly before opening. Reconstitute in 200 µL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material.
- Storage Instructions After reconstitution keep aliquots at -20°C for higher stability or at 2-8°C with an appropriate antibacterial agent. Glycerol (1:1) may be added for additional stability. Avoid repetitive freeze/thaw cycles.
- Batch Number Please see item label.
- Expiration Date 12 months after date of receipt (unopened vial).
- Alternative Names Protein jagged-1; Jagged 1; hJ1; CD339 antigen; JAG1; JAGL1;
- Uniprot Number P78504
- Uniprot Number/Name P78504 (JAG1_HUMAN)
- Scientific Background The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for multiple Notch receptors involved in the mediation of Notch signalling. It may be involved in cell-fate decision during hematopoiesis and seems to be involved in early and late stages of mammalian cardiovascular development. JAG1 is a trans membrane protein that is widely expressed in adult and fetal tissues. Mutations that alter the jagged 1 protein cause Alagille syndrome which is an autosomal dominant multisysstem disorder. Defects in JAG1 are also the cause of tetralogy of Fallot (TOF) which is a congenital heart anomaly.
- Shipping Temperature 25°C (ambient)
- UNSPSC CODE 41116161
- Regulatory Status For research use only.
