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Ectoderm-heural cortex protein 1 (ENC-1), Mouse Monoclonal Antibody
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Catalog Number
M-876
- Product Name Ectoderm-heural cortex protein 1 (ENC-1), Mouse Monoclonal Antibody
- Product Description Mouse anti-Ectoderm-heural cortex protein 1 (ENC-1) Monoclonal Antibody (Unconjugated), suitable for WB, ELISA.
- Alternative Names Ectodermal-neural cortex protein 1; p53-induced gene 10 protein; Nuclear matrix protein NRP/B; ENC1; NRPB; PIG10
- Application(s) ELISA, WB
- Antibody Host Mouse
- Antibody Type Monoclonal
- Specificity Specificity has been confirmed by WB and direct ELISA against the antigen. Human. Other species have not been tested.
- Species Reactivity Human
- Immunogen Description Partial recombinant human ENC-1 (amino acids 17-98) with a GST tag.
- Conjugate Unconjugated
- Purity Description Protein G purified immunoglobulin
- Regulatory Status For research use only.
Product Info
- Product Description Mouse anti-Ectoderm-heural cortex protein 1 (ENC-1) Monoclonal Antibody (Unconjugated), suitable for WB, ELISA.
- Application(s) ELISA, WB
- Application Details This antibody is recommended for WB, and sandwich ELISA. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
- Target Ectoderm-heural cortex protein 1 (ENC-1)
- Specificity Specificity has been confirmed by WB and direct ELISA against the antigen. Human. Other species have not been tested.
- Target Host Species Human
- Species Reactivity Human
- Antibody Host Mouse
- Antibody Type Monoclonal
- Antibody Isotype IgG
- Clone Name 3B1
- Conjugate Unconjugated
- Immunogen Description Partial recombinant human ENC-1 (amino acids 17-98) with a GST tag.
- Purity Description Protein G purified immunoglobulin
- Format Lyophilized from PBS pH 7.2
- Reconstitution Instructions Spin vial briefly before opening. Reconstitute in 100 µL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material.
- Storage Instructions After reconstitution keep aliquots at -20°C for higher stability or at 2-8°C with an appropriate antibacterial agent. Glycerol (1:1) may be added for additional stability. Avoid repetitive freeze/thaw cycles.
- Batch Number Please see item label.
- Expiration Date 12 months after date of receipt (unopened vial).
- Alternative Names Ectodermal-neural cortex protein 1; p53-induced gene 10 protein; Nuclear matrix protein NRP/B; ENC1; NRPB; PIG10
- Uniprot Number O14682
- Uniprot Number/Name O14682 (ENC1_HUMAN)
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Scientific Background
ENC-1 is an actin-binding protein involved in the regulation of neuronal process formation and in differentiation of neural crest cells. It is a substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target protein. It is detected in fetal brain tissue, moderate expression in fetal heart, lung and kidney. It is highly exprssed in adult brain, especially in the hippocampus and amygdala, and spinal cord. It is dramatically up-regulated upon neuronal differentiation.
- Shipping Temperature 25°C (ambient)
- UNSPSC CODE 41116161
- Regulatory Status For research use only.
