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Caldesmon (CDM), Mouse Monoclonal Antibody
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Catalog Number
M-974
- Product Name Caldesmon (CDM), Mouse Monoclonal Antibody
- Product Description Mouse anti-Caldesmon (CDM) Monoclonal Antibody (Unconjugated), suitable for WB, IHC-Frozen, IHC-Paraffin-embedded.
- Alternative Names CAD; CDM; CALD1; CALD1_HUMAN; h-CD;
- Application(s) IHC-Frozen, IHC-Paraffin-embedded, WB
- Antibody Host Mouse
- Antibody Type Monoclonal
- Specificity The specificity of this antibody has been confirmed by WB and IHC against the antigen. Human; mouse; rat
- Species Reactivity Human, Mouse, Rat
- Immunogen Description Human uterus smooth muscle extract
- Conjugate Unconjugated
- Purity Description IgG
- Regulatory Status For research use only.
Product Info
- Product Description Mouse anti-Caldesmon (CDM) Monoclonal Antibody (Unconjugated), suitable for WB, IHC-Frozen, IHC-Paraffin-embedded.
- Application(s) IHC-Frozen, IHC-Paraffin-embedded, WB
- Application Details Immunohistochemistry (IHC) and Western Blotting (WB). A concentration of 1.0-2.0 µg/mL is recommended for WB. Human caldesmon has a predicted length of 793 residues and a MW of 93 kDa. A concentration of 2.0-4.0 µg/mL is recommended to detect caldesmon in formalin fixed and paraffin embedded tissues. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
- Target Caldesmon (CDM)
- Specificity The specificity of this antibody has been confirmed by WB and IHC against the antigen. Human; mouse; rat
- Target Host Species Human
- Species Reactivity Human, Mouse, Rat
- Antibody Host Mouse
- Antibody Type Monoclonal
- Antibody Isotype IgG
- Clone Name CD-7
- Conjugate Unconjugated
- Immunogen Description Human uterus smooth muscle extract
- Purity Description IgG
- Format Lyophilized from 1.2% sodium acetate, 2 mg BSA, 0.01 mg NaN3
- Reconstitution Instructions Spin vial briefly before opening. Reconstitute in 1 mL of sterile-filtered PBS (pH 7.4) to achieve an antibody concentration of 100 µg/mL. Centrifuge to remove any insoluble material.
- Storage Instructions At least 12 months after purchase at 2-8°C (lyophilized formulations). After reconstitution, aliquot and store at -20°C for a higher stability. Avoid freeze-thaw cycles.
- Batch Number Please see item label.
- Expiration Date 12 months after date of receipt (unopened vial).
- Alternative Names CAD; CDM; CALD1; CALD1_HUMAN; h-CD;
- Uniprot Number Q05682
- Uniprot Number/Name Q05682 (CALD1_HUMAN)
- Scientific Background Caldesmon is an actin and myosin binding protein. It plays a major role in the regulation of smooth muscle and non-muscle contractile events. At least 5 isoforms are known from alternate splicing. High molecular weight h-caldesmon (isoform 1) of 120-150 kDa is predominantly expressed in smooth muscles. Lower molecular weight caldesmon l-caldesmon (isoforms 2,3,4 and 5) of 61-70 kDa is more abundant in non-muscle tissues and cells. This antibody reacts specifically with h-caldesmon.
- Shipping Temperature 25°C (ambient)
- UNSPSC CODE 41116161
- Regulatory Status For research use only.