1800 605-5127
+61 (0)8 8352 7711
Cysteini-rich motor neuron 1 protein (CRIM1), Mouse Monoclonal Antibody
As low as
US$417.00
Only %1 left
Catalog Number
M-817
- Product Name Cysteini-rich motor neuron 1 protein (CRIM1), Mouse Monoclonal Antibody
- Product Description Mouse anti-Cysteini-rich motor neuron 1 protein (CRIM1) Monoclonal Antibody (Unconjugated), suitable for WB, IHC-Frozen, ELISA.
- Alternative Names Cysteine-rich motor neuron 1 protein; cysteine-rich repeat-containing protein S52; CRIM1
- Application(s) ELISA, IHC-Frozen, WB
- Antibody Host Mouse
- Antibody Type Monoclonal
- Specificity The specificity of this antibody has been confirmed by WB and ELISA against the antigen. No other species have been tested.
- Species Reactivity Human
- Immunogen Description A partial recombinant human CRIM1 protein (amino acids 36 to 145) with a GST tag.
- Conjugate Unconjugated
- Purity Description Protein G purified immunoglobulin
- Regulatory Status For research use only.
Product Info
- Product Description Mouse anti-Cysteini-rich motor neuron 1 protein (CRIM1) Monoclonal Antibody (Unconjugated), suitable for WB, IHC-Frozen, ELISA.
- Application(s) ELISA, IHC-Frozen, WB
- Application Details This antibody is recommended for IHC at a dilution of 3 µg/mL. It is also recommended for sandwich ELISA with a detection limit for the recombinant GST tagged CRIM1 protein of 0.03 ng/mL. This antibody is useful for WB analysis. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
- Target Cysteini-rich motor neuron 1 protein (CRIM1)
- Specificity The specificity of this antibody has been confirmed by WB and ELISA against the antigen. No other species have been tested.
- Target Host Species Human
- Species Reactivity Human
- Antibody Host Mouse
- Antibody Type Monoclonal
- Antibody Isotype IgG
- Clone Name 6E4
- Conjugate Unconjugated
- Immunogen Description A partial recombinant human CRIM1 protein (amino acids 36 to 145) with a GST tag.
- Purity Description Protein G purified immunoglobulin
- Format Lyophilized from PBS pH 7.2
- Reconstitution Instructions Spin vial briefly before opening. Reconstitute in 100 µL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material.
- Storage Instructions After reconstitution keep aliquots at -20°C for higher stability or at 2-8°C with an appropriate antibacterial agent. Glycerol (1:1) may be added for additional stability. Avoid repetitive freeze/thaw cycles.
- Batch Number Please see item label.
- Expiration Date 12 months after date of receipt (unopened vial).
- Alternative Names Cysteine-rich motor neuron 1 protein; cysteine-rich repeat-containing protein S52; CRIM1
- Uniprot Number Q9NZV1
- Uniprot Number/Name Q9NZV1 (CRIM1_HUMAN)
-
Scientific Background
CRIM1 may participate in CNS development by interacting with growth factors involved in motor neuron differentiation and survival. It also has a potential role in capillary formation and maintenance during angiogenesis. It also affects BMP processing and delivery to the cell surface. CRIM1 interacts with BMP4 and BMP7. It localises to the cell membrane and is expressed in a number of tissues including the pancreas, kidney, skeletal muscle, lung, placenta, brain, heart, spleen, liver, small intestine and blood vessels. The unprocessed precursor has a length of 1036 amino acids and a predicted molecular weight of 113.7KDa. CRIM1 contains four antistatin-like domains, one IGFBP N-terminal domain and six VWFC domains. It is also N-glycosylated.
- Shipping Temperature 25°C (ambient)
- UNSPSC CODE 41116161
- Regulatory Status For research use only.
