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Roundabout homolog 1, Mouse Monoclonal Antibody
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Catalog Number
M-862
- Product Name Roundabout homolog 1, Mouse Monoclonal Antibody
- Product Description Mouse anti-Roundabout homolog 1 Monoclonal Antibody (Unconjugated), suitable for WB, ELISA.
- Alternative Names H-Robo-1; Deleted in U twenty twenty; ROBO1; DUTT1
- Application(s) ELISA, WB
- Antibody Host Mouse
- Antibody Type Monoclonal
- Specificity Specificity has been confirmed by WB and direct ELISA against the antigen. Human. Other species have not been tested.
- Species Reactivity Human
- Immunogen Description Partial recombinant human Roundabout homolog 1 (amino acids 491-589) with a GST tag.
- Conjugate Unconjugated
- Purity Description Protein G purified immunoglobulin
- Regulatory Status For research use only.
Product Info
- Product Description Mouse anti-Roundabout homolog 1 Monoclonal Antibody (Unconjugated), suitable for WB, ELISA.
- Application(s) ELISA, WB
- Application Details This antibody is recommended for WB and sandwich ELISA. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
- Target Roundabout homolog 1
- Specificity Specificity has been confirmed by WB and direct ELISA against the antigen. Human. Other species have not been tested.
- Target Host Species Human
- Species Reactivity Human
- Antibody Host Mouse
- Antibody Type Monoclonal
- Antibody Isotype IgG
- Clone Name 2G6
- Conjugate Unconjugated
- Immunogen Description Partial recombinant human Roundabout homolog 1 (amino acids 491-589) with a GST tag.
- Purity Description Protein G purified immunoglobulin
- Format Lyophilized from PBS pH 7.2
- Reconstitution Instructions Spin vial briefly before opening. Reconstitute in 100 µL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material.
- Storage Instructions After reconstitution keep aliquots at -20°C for higher stability or at 2-8°C with an appropriate antibacterial agent. Glycerol (1:1) may be added for additional stability. Avoid repetitive freeze/thaw cycles.
- Batch Number Please see item label.
- Expiration Date 12 months after date of receipt (unopened vial).
- Alternative Names H-Robo-1; Deleted in U twenty twenty; ROBO1; DUTT1
- Uniprot Number Q9Y6N7
- Uniprot Number/Name Q9Y6N7 (ROBO1_HUMAN)
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Scientific Background
Roundabout homolog 1 belongs to the neural adhesion molecule (NCAM) family of receptors. It is a receptor for SLIT1 and SLIT2 which are thought to act as a molecular guidance cue in cellular migration, including axonal navigation at the ventral midline of the neural tube and projection of axons to different regions during neuronal development. It may be required for lung development. There are three named isoforms. It is widely expressed, with the exception of kidney. Defects in Roundabout homolog 1 may be a cause of breast and lung cancer.
- Shipping Temperature 25°C (ambient)
- UNSPSC CODE 41116161
- Regulatory Status For research use only.
