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Semaphorin-3A, Mouse Monoclonal Antibody
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Catalog Number
M-886
- Product Name Semaphorin-3A, Mouse Monoclonal Antibody
- Product Description Mouse anti-Semaphorin-3A Monoclonal Antibody (Unconjugated), suitable for WB, ELISA.
- Alternative Names Semaphorin III; Sema III; SEMA3A; SEMAD
- Application(s) ELISA, WB
- Antibody Host Mouse
- Antibody Type Monoclonal
- Specificity Specificity has been confirmed by WB and direct ELISA against the antigen. Human. Other species have not been tested.
- Species Reactivity Human
- Immunogen Description Partial recombinant human Semaphorin 3A (672-770) with a GST tag.
- Conjugate Unconjugated
- Purity Description Protein G purified immunoglobulin
- Regulatory Status For research use only.
Product Info
- Product Description Mouse anti-Semaphorin-3A Monoclonal Antibody (Unconjugated), suitable for WB, ELISA.
- Application(s) ELISA, WB
- Application Details This antibody is recommended for WB, and ELISA. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
- Target Semaphorin-3A
- Specificity Specificity has been confirmed by WB and direct ELISA against the antigen. Human. Other species have not been tested.
- Target Host Species Human
- Species Reactivity Human
- Antibody Host Mouse
- Antibody Type Monoclonal
- Antibody Isotype IgG2a, kappa
- Clone Name 5G9
- Conjugate Unconjugated
- Immunogen Description Partial recombinant human Semaphorin 3A (672-770) with a GST tag.
- Purity Description Protein G purified immunoglobulin
- Format Lyophilized from PBS pH 7.4
- Reconstitution Instructions Spin vial briefly before opening. Reconstitute in 50 µL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material.
- Storage Instructions Store lyophilized antibody at 2-8ºC. After reconstitution keep aliquots at -20°C for higher stability or at 2-8°C with an appropriate antibacterial agent. Glycerol (1:1) may be added for additional stability. Avoid repetitive freeze/thaw cycles.
- Batch Number Please see item label.
- Expiration Date 12 months after date of receipt (unopened vial).
- Alternative Names Semaphorin III; Sema III; SEMA3A; SEMAD
- Uniprot Number Q14563
- Uniprot Number/Name Q14563 (SEM3A_HUMAN)
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Scientific Background
Semaphorin-3A is a secreted protein that induces the collapse and paralysis of neuronal growth cones. It could serve as a ligand that guides specific growth cones by a motility-inhibiting mechanism. It Binds to the complex neuropilin-1/plexin-1. Increased expression of this protein is associated with schizophrenia and is seen in a variety of human tumor cell lines. Also, aberrant release of this protein is associated with the progression of Alzheimer's disease.
- Shipping Temperature 25°C (ambient)
- UNSPSC CODE 41116161
- Regulatory Status For research use only.
