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Spectrin (alpha & beta), Mouse Monoclonal Antibody
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Catalog Number
M-1222
- Product Name Spectrin (alpha & beta), Mouse Monoclonal Antibody
- Product Description Mouse anti-Spectrin (alpha & beta) Monoclonal Antibody (Unconjugated), suitable for WB.
- Alternative Names Spectrin alpha chain, erythrocyte; Erythroid alpha-spectrin; SPTA1; SPTA; Spectrin beta chain, erythrocyte; Beta-I spectrin; SPTB; SPTB1;
- Application(s) WB
- Antibody Host Mouse
- Antibody Type Monoclonal
- Specificity The specificity of this antibody has been confirmed by WB against the antigen. Human;
- Species Reactivity Human
- Immunogen Description Human erythrocyte Spectrin
- Conjugate Unconjugated
- Purity Description IgG
- Regulatory Status For research use only.
Product Info
- Product Description Mouse anti-Spectrin (alpha & beta) Monoclonal Antibody (Unconjugated), suitable for WB.
- Application(s) WB
- Application Details Western Blotting (WB). A concentration of 2.0-4.0 µg/mL is recommended for cells and tissues. Human Spectrin alpha chain (isoform 1) has a predicted length of 2,419 residues and a MW of 280 kDa. Human Spectrin beta chain (isoform 1) has a predicted length of 2,137 residues and a MW of 246 kDa.
- Target Spectrin (alpha & beta)
- Specificity The specificity of this antibody has been confirmed by WB against the antigen. Human;
- Target Host Species Human
- Species Reactivity Human
- Antibody Host Mouse
- Antibody Type Monoclonal
- Antibody Isotype IgG
- Clone Name Spe1/2
- Conjugate Unconjugated
- Immunogen Description Human erythrocyte Spectrin
- Purity Description IgG
- Format Lyophilized from 1.2% sodium acetate, 2 mg BSA, 0.01 mg NaN3
- Reconstitution Instructions Spin vial briefly before opening. Reconstitute in 1 mL of sterile-filtered PBS (pH 7.4) to achieve an antibody concentration of 100 µg/mL. Centrifuge to remove any insoluble material.
- Storage Instructions At least 12 months after purchase at 2-8°C (lyophilized formulations). After reconstitution, aliquot and store at -20°C for a higher stability. Avoid freeze-thaw cycles.
- Batch Number Please see item label.
- Expiration Date 12 months after date of receipt (unopened vial).
- Alternative Names Spectrin alpha chain, erythrocyte; Erythroid alpha-spectrin; SPTA1; SPTA; Spectrin beta chain, erythrocyte; Beta-I spectrin; SPTB; SPTB1;
- Uniprot Number P02549; P11277
-
Uniprot Number/Name
P02549 (SPTA1_HUMAN)
P11277 (SPTB1_HUMAN) - Scientific Background Spectrin is a major component of the cytoskeletal superstructure of the erythrocyte plasma membrane. Spectrin is composed of non-homologous alpha and beta chains which aggregate to form dimers, tetramers and higher polymers. Multiple isoforms of alpha and beta chains are produced by alternative splicing.
- Shipping Temperature 25°C (ambient)
- UNSPSC CODE 41116161
- Regulatory Status For research use only.