Product DescriptionMouse anti-Dihydropyrimidinase-related protein 4 (DRP-4) Polyclonal Antibody (Unconjugated), suitable for WB, ELISA.
Application(s)ELISA, WB
Application DetailsThis antibody is recommended for WB and ELISA. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
TargetDihydropyrimidinase-related protein 4 (DRP-4)
SpecificitySpecificity has been confirmed by WB and direct ELISA against the antigen. Human. Other species have not been tested.
Target Host SpeciesHuman
Species ReactivityHuman
Antibody HostMouse
Antibody TypePolyclonal
Antibody IsotypeMixed
ConjugateUnconjugated
Immunogen DescriptionPartial recombinant human DRP-4 (461-559) with a GST tag.
Purity DescriptionWhole serum
FormatLiquid. 50% glycerol
Storage InstructionsKeep aliquots at -20°C for higher stability or at 2-8°C with an appropriate antibacterial agent. Avoid repetitive freeze/thaw cycles.
Batch NumberPlease see item label.
Expiration Date12 months after date of receipt (unopened vial).
Alternative NamesDihydropyrimidinase-relate protein 3; Collapsin response mediator protein 3; CRMP-3; UNC33-like phosphoprotein 4; ULIP4 protein; DPYSL4; CRMP3; ULIP4
DRP-4 belongs to the hydantoinase/dihydropyrimidase subfamily. It is required for signalling by class 3 semaphorins and remodelling of the cytoskeleton. It also plays a role in axon guidance, neuronal growth cone collapse and cell migration. It exists as homotetramer and a heterotetramer. Antibodies against post-translationally modified DPR-4 are present in sera from patients with paraneoplastic neurological diseases.