Product DescriptiongoogleMouse anti-Pro-glucagon Monoclonal Antibody (Unconjugated), suitable for IHC-Frozen, IHC-Paraffin-embedded.
Alternative NamesGLP1; GLP2; GRPP; GCG;
Application(s)IHC-Frozen, IHC-Paraffin-embedded
Antibody HostMouse
Antibody TypeMonoclonal
SpecificityThis anti-Glucagon Gcg Antibody was tested in IHC applications. Reacts with pancreatic glucagon. This antibody reacts with Human, Mouse, Rabbit, Rat., not recommended for detection of enteroglucagon.
Species ReactivityHuman, Pig, Rat
Immunogen DescriptionPolymerized porcine glucagon
ConjugateUnconjugated
Purity DescriptionMouse IgG in 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as a preservative
Product DescriptionMouse anti-Pro-glucagon Monoclonal Antibody (Unconjugated), suitable for IHC-Frozen, IHC-Paraffin-embedded.
Application(s)IHC-Frozen, IHC-Paraffin-embedded
Application DetailsImmunohistochemistry (IHC). A concentration of 1.0-2.0 µg/mL is recommended to detect the protein in paraffin-embedded tissues. Antigen retrieval by Heat is required. Biosensis recommends that optimal dilutions/concentrations should be determined by the end user.
TargetPro-glucagon
SpecificityThis anti-Glucagon Gcg Antibody was tested in IHC applications. Reacts with pancreatic glucagon. This antibody reacts with Human, Mouse, Rabbit, Rat., not recommended for detection of enteroglucagon.
Target Host SpeciesPig
Species ReactivityHuman, Pig, Rat
Antibody HostMouse
Antibody TypeMonoclonal
Antibody IsotypeIgG
Clone NameIMD-7
ConjugateUnconjugated
Immunogen DescriptionPolymerized porcine glucagon
Purity DescriptionMouse IgG in 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as a preservative
FormatLyophilized solution containing 1.2% sodium acetate, 2 mg BSA, with 0.01 mg NaN3 as a preservative
Reconstitution InstructionsSpin vial briefly before opening. Reconstitute in 1 mL of sterile-filtered PBS (pH 7.4) to achieve an antibody concentration of 100 µg/mL. Centrifuge to remove any insoluble material.
Storage InstructionsLyphoilized 2-8°C. After reconstitution, aliquot and store at -20°C for up to 6 months. Avoid freeze-thaw cycles
Batch NumberPlease see item label.
Expiration Date12 months after date of receipt (unopened vial).
Scientific BackgroundThe glucagon preproprotein is cleaved into a number of distinct peptides that include glucagon, glucagon-like peptide 1 (GLP-1) and glucagon-like peptide 2 (GLP-2). Glucagon has a key role in glucose metabolism and homeostasis. The release of glucagon is stimulated by hypoglycemia and regulates the level of blood glucose by increasing gluconeogenesis and decreasing glycolysis.