Beta casein protein, Rabbit Polyclonal Antibody

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Catalog Number
R-1794

    Product Info

  • Product Name Beta casein protein, Rabbit Polyclonal Antibody
  • Product Description google Rabbit anti-Beta casein protein Polyclonal Antibody (Unconjugated), suitable for WB, ELISA.
  • Application(s) ELISA, WB
  • Antibody Host Rabbit
  • Antibody Type Polyclonal
  • Specificity Bovine beta-casein. Detects both A1 and A2 beta-casein isoforms.
  • Species Reactivity Bovine
  • Immunogen Description Bovine beta-casein peptides
  • Conjugate Unconjugated
  • Purity Description Affinity purified
  • Regulatory Status For research use only.

    Specifications

  • Product Description Rabbit anti-Beta casein protein Polyclonal Antibody (Unconjugated), suitable for WB, ELISA.
  • Related Products A1 Beta casein (A1), Bovine, ELISA assay
    A2 Beta casein (A2), Bovine, ELISA assay
    Casein, A2 beta, Chicken Polyclonal Antibody
    Casein, A1 beta, Chicken Polyclonal Antibody
    Casein, bovine beta A1, Purified Protein
    Casein, bovine beta A2, Purified Protein
  • Application(s) ELISA, WB
  • Application Details ELISA and western blotting (1:5,000 - 1: 20,000). Do not use skim milk for blocking and dilution of assay reagents, BSA is recommended. Biosensis recommends that optimal working dilutions should be determined by the end user.
  • Target Beta casein protein
  • Specificity Bovine beta-casein. Detects both A1 and A2 beta-casein isoforms.
  • Target Host Species Bovine
  • Species Reactivity Bovine
  • Antibody Host Rabbit
  • Antibody Type Polyclonal
  • Antibody Isotype IgG
  • Conjugate Unconjugated
  • Immunogen Description Bovine beta-casein peptides
  • Purity Description Affinity purified
  • Physical State Liquid.
  • Format Liquid in PBS, pH 7.4. Refer to the product label for antibody concentration.
  • Storage Instructions Spin vial briefly before opening and centrifuge to remove any insoluble material. After opening maintain at -20°C in undiluted aliquots for up to 6 months. For short-term storage, keep aliquot at 2-8°C for up to one week. Avoid repeated freeze-thaw cycles.
  • Batch Number Please see item label.
  • Expiration Date 12 months after date of receipt (unopened vial).
  • Uniprot Number P02666
  • Uniprot Number/Name P02666 (CASB_BOVIN)
  • Scientific Background Beta-casein has an important role in determination of the surface properties of the casein micelles. it is cleaved into 3 chains (casoparan, casohypotensin and antioxidant peptide). Casoparan acts as a macrophage activator, increasing the phagocytic activity of macrophages and peroxide release from macrophages. It also acts as a bradykinin-potentiating peptide. Casohypotensin acts as a bradykinin-potentiating peptide and induces hypotension in rats. Acts as a strong competitive inhibitor of endo-oligopeptidase A. Antioxidant peptide has antioxidant activity (ref: uniprot.org.).

    Bovine milk contains two types of beta-casein protein, A2 or A1. Recent studies have shown that milk containing the A1 beta casein protein can contribute to issues including gastrointestinal discomfort after ingestion. There is some evidence of a link between ingestion of A1 beta casein protein and the development of Type 1 diabetes.
  • Shipping Temperature 2-8°C (on cold packs)
  • UNSPSC CODE 41116161
  • Regulatory Status For research use only.

    Images, Protocols & SDS

  • Western Blot analysis of bovine milk (0.5 µL/lane; Lane 1 and 2). Primary antibody was used at 1:10,000 dilution. BSA was used in blocking and dilution buffer.

  • SDS Link

    SDS_R-1794-100_as_at_Jan2022.pdf

    Citations & References

  • Specific References Indyk HE et al. (2021) The determination of intact β-casein in milk products by biosensor immunoassay. J. Food Compos. Anal. 101:103946 Application: Immunoassay.