Product DescriptionMouse anti-LIM/homeobox protein 1.2 (LMX-1.2) Polyclonal Antibody (Unconjugated), suitable for WB, ELISA.
Application(s)ELISA, WB
Application DetailsThis antibody is recommended for WB and ELISA. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
TargetLIM/homeobox protein 1.2 (LMX-1.2)
SpecificitySpecificity has been confirmed by WB and direct ELISA against the antigen. Human. Other species have not been tested.
Target Host SpeciesHuman
Species ReactivityHuman
Antibody HostMouse
Antibody TypePolyclonal
Antibody IsotypeMixed
ConjugateUnconjugated
Immunogen DescriptionPartial recombinant human LMX-1.2 (1-110) with a GST tag.
Purity DescriptionWhole serum
FormatLiquid. 50% glycerol
Storage InstructionsKeep aliquots at -20°C for higher stability or at 2-8°C with an appropriate antibacterial agent. Avoid repetitive freeze/thaw cycles.
Batch NumberPlease see item label.
Expiration Date12 months after date of receipt (unopened vial).
Alternative NamesLIM homeobox transcription factor 1 beta; LIM/homeobox protein LMX1B; LIM/homeobox protein 1.2; LMX-1.2; LMX1B
LMX-1.2 is essential for the specification of dorsal limb fate. It is expressed in most of tissues, with highest levels in testis, thyroid, duodenum, skeletal muscle, and pancreatic islets. Defects in LMX-1.2 are the cause of nail-patella syndrome (NPS), also known as Onychoosteodysplasia. NPS is a disease that causes abnormal skeletal patterning and renal dysplasia. LIM homeodomain proteins are characterised by the presence of 2 tandem cysteine/histidine-rich, zinc-binding LIM domains.