Product NameCaspase recruitment domain-containing protein 16 (CARD16), Goat Polyclonal Antibody
Product DescriptiongoogleGoat anti-Caspase recruitment domain-containing protein 16 (CARD16) Polyclonal Antibody (Unconjugated), suitable for Pep-ELISA, ICC, FC.
Alternative NamesCARD16; COP; CARD only protein; PSEUDO-ICE; COP1; caspase-1 dominant-negative inhibitor pseudo-ICE; pseudo interleukin-1beta converting enzyme; caspase recruitment domain family, member 16; Pseudo-IL1B-converting enzyme;
Application(s)FC, ICC, Pep-ELISA
Antibody HostGoat
Antibody TypePolyclonal
SpecificityReacts with COP1 / PSEUDO-ICE (Isofom 2) from Human. This antibody is expected to recognize isoform 2 (NP_443121.1) only. In addition there may be cross-reaction with INCA (GeneID 440068; NP_001007233.1).
Species ReactivityHuman
Immunogen DescriptionA synthetic peptide consisting of amino acids, C-ETLGLSAGPIPGN
ConjugateUnconjugated
Purity DescriptionPurified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Product DescriptionGoat anti-Caspase recruitment domain-containing protein 16 (CARD16) Polyclonal Antibody (Unconjugated), suitable for Pep-ELISA, ICC, FC.
Application(s)FC, ICC, Pep-ELISA
Application DetailsELISA (1:4000), Immunofluorescence (10 µg/mL), Flow Cytometry (10 µg/mL). Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
TargetCaspase recruitment domain-containing protein 16 (CARD16)
SpecificityReacts with COP1 / PSEUDO-ICE (Isofom 2) from Human. This antibody is expected to recognize isoform 2 (NP_443121.1) only. In addition there may be cross-reaction with INCA (GeneID 440068; NP_001007233.1).
Target Host SpeciesHuman
Species ReactivityHuman
Antibody HostGoat
Antibody TypePolyclonal
Antibody IsotypeIgG
ConjugateUnconjugated
Immunogen DescriptionA synthetic peptide consisting of amino acids, C-ETLGLSAGPIPGN
SequenceETLGLSAGPIPGN
Purity DescriptionPurified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
FormatLiquid antibody. Supplied at 0.5 mg/mL in Tris saline, 0.02% sodium azide, pH 7.3 with 0.5% bovine serum albumin.
Storage InstructionsUpon receipt, aliquot and store at -20°C long-term. Store at 2-8°C short-term (up to 2 weeks). Minimize freezing and thawing.
Batch NumberPlease see item label.
Expiration Date12 months after date of receipt (unopened vial).
Alternative NamesCARD16; COP; CARD only protein; PSEUDO-ICE; COP1; caspase-1 dominant-negative inhibitor pseudo-ICE; pseudo interleukin-1beta converting enzyme; caspase recruitment domain family, member 16; Pseudo-IL1B-converting enzyme;
Scientific BackgroundCaspase inhibitor. Acts as a regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-interleukin-1 beta (IL1B) and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes.