SpecificityReacts with FOXP3 / SCURFIN from Human. This antibody is expected to recognize both reported isoforms (NP_054728.2 and NP_001107849.1).
Species ReactivityHuman
Immunogen DescriptionA synthetic peptide consisting of amino acids, SQRPSRCSNPTPGP
ConjugateUnconjugated
Purity DescriptionPurified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Application DetailsPeptide ELISA (1:2000), Flow Cytometry (10 µg/mL). Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
TargetForkhead box protein P3 (FOXP3)
SpecificityReacts with FOXP3 / SCURFIN from Human. This antibody is expected to recognize both reported isoforms (NP_054728.2 and NP_001107849.1).
Target Host SpeciesHuman
Species ReactivityHuman
Antibody HostGoat
Antibody TypePolyclonal
Antibody IsotypeIgG
ConjugateUnconjugated
Immunogen DescriptionA synthetic peptide consisting of amino acids, SQRPSRCSNPTPGP
SequenceCSNPTPGP
Purity DescriptionPurified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
FormatLiquid antibody. Supplied at 0.5 mg/mL in Tris saline, 0.02% sodium azide, pH 7.3 with 0.5% bovine serum albumin.
Storage InstructionsUpon receipt, aliquot and store at -20°C long-term. Store at 2-8°C short-term (up to 2 weeks). Minimize freezing and thawing.
Batch NumberPlease see item label.
Expiration Date12 months after date of receipt (unopened vial).
Scientific BackgroundTranscriptional regulator which is crucial for the development and inhibitory function of regulatory T-cells (Treg). Plays an essential role in maintaining homeostasis of the immune system by allowing the acquisition of full suppressive function and stability of the Treg lineage, and by directly modulating the expansion and function of conventional T-cells (Uniprot).