Product NameKelch-like ECH-associated protein 1 (KEAP1), Goat Polyclonal Antibody
Product DescriptiongoogleGoat anti-Kelch-like ECH-associated protein 1 (KEAP1) Polyclonal Antibody (Unconjugated), suitable for Pep-ELISA, FC.
Alternative NamesKEAP1; kelch-like ECH-associated protein 1; INrf2; KIAA0132; KLHL19; MGC10630; MGC1114; MGC20887; MGC4407; MGC9454; cytosolic inhibitor of Nrf2; kelch-like protein 19
Application(s)FC, Pep-ELISA
Antibody HostGoat
Antibody TypePolyclonal
SpecificityReacts with KEAP1 (aa381-394) from Human. Reported variants represent identical protein: NP_036421.2, NP_987096.1.
Species ReactivityBovine, Dog, Human, Mouse, Pig, Rat
Immunogen DescriptionA synthetic peptide consisting of amino acids, C-NNSPDGNTDSSALD
ConjugateUnconjugated
Purity DescriptionPurified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Product DescriptionGoat anti-Kelch-like ECH-associated protein 1 (KEAP1) Polyclonal Antibody (Unconjugated), suitable for Pep-ELISA, FC.
Application(s)FC, Pep-ELISA
Application DetailsPeptide ELISA (1:8,000), Flow Cytometry (10 µg/mL). Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
TargetKelch-like ECH-associated protein 1 (KEAP1)
SpecificityReacts with KEAP1 (aa381-394) from Human. Reported variants represent identical protein: NP_036421.2, NP_987096.1.
Target Host SpeciesHuman
Species ReactivityBovine, Dog, Human, Mouse, Pig, Rat
Antibody HostGoat
Antibody TypePolyclonal
Antibody IsotypeIgG
ConjugateUnconjugated
Immunogen DescriptionA synthetic peptide consisting of amino acids, C-NNSPDGNTDSSALD
SequenceNNSPDGNTDSSALD
Purity DescriptionPurified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
FormatLiquid antibody. Supplied at 0.5 mg/mL in Tris saline, 0.02% sodium azide, pH 7.3 with 0.5% bovine serum albumin.
Storage InstructionsUpon receipt, aliquot and store at -20°C long-term. Store at 2-8°C short-term (up to 2 weeks). Minimize freezing and thawing.
Batch NumberPlease see item label.
Expiration Date12 months after date of receipt (unopened vial).
Alternative NamesKEAP1; kelch-like ECH-associated protein 1; INrf2; KIAA0132; KLHL19; MGC10630; MGC1114; MGC20887; MGC4407; MGC9454; cytosolic inhibitor of Nrf2; kelch-like protein 19
Scientific BackgroundGrowth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin (PubMed:26599395). Required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta. Required for normal blood vessel development, and for normal development of kidney glomeruli. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers with PDGFA