Kelch-like ECH-associated protein 1 (KEAP1), Goat Polyclonal Antibody

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Catalog Number
G-1904

    Product Info

  • Product Name Kelch-like ECH-associated protein 1 (KEAP1), Goat Polyclonal Antibody
  • Product Description google Goat anti-Kelch-like ECH-associated protein 1 (KEAP1) Polyclonal Antibody (Unconjugated), suitable for Pep-ELISA, FC.
  • Alternative Names KEAP1; kelch-like ECH-associated protein 1; INrf2; KIAA0132; KLHL19; MGC10630; MGC1114; MGC20887; MGC4407; MGC9454; cytosolic inhibitor of Nrf2; kelch-like protein 19
  • Application(s) FC, Pep-ELISA
  • Antibody Host Goat
  • Antibody Type Polyclonal
  • Specificity Reacts with KEAP1 (aa381-394) from Human. Reported variants represent identical protein: NP_036421.2, NP_987096.1.
  • Species Reactivity Bovine, Dog, Human, Mouse, Pig, Rat
  • Immunogen Description A synthetic peptide consisting of amino acids, C-NNSPDGNTDSSALD
  • Conjugate Unconjugated
  • Purity Description Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • Regulatory Status For research use only.

    Specifications

  • Product Description Goat anti-Kelch-like ECH-associated protein 1 (KEAP1) Polyclonal Antibody (Unconjugated), suitable for Pep-ELISA, FC.
  • Application(s) FC, Pep-ELISA
  • Application Details Peptide ELISA (1:8,000), Flow Cytometry (10 µg/mL). Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
  • Target Kelch-like ECH-associated protein 1 (KEAP1)
  • Specificity Reacts with KEAP1 (aa381-394) from Human. Reported variants represent identical protein: NP_036421.2, NP_987096.1.
  • Target Host Species Human
  • Species Reactivity Bovine, Dog, Human, Mouse, Pig, Rat
  • Antibody Host Goat
  • Antibody Type Polyclonal
  • Antibody Isotype IgG
  • Conjugate Unconjugated
  • Immunogen Description A synthetic peptide consisting of amino acids, C-NNSPDGNTDSSALD
  • Sequence NNSPDGNTDSSALD
  • Purity Description Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • Format Liquid antibody. Supplied at 0.5 mg/mL in Tris saline, 0.02% sodium azide, pH 7.3 with 0.5% bovine serum albumin.
  • Storage Instructions Upon receipt, aliquot and store at -20°C long-term. Store at 2-8°C short-term (up to 2 weeks). Minimize freezing and thawing.
  • Batch Number Please see item label.
  • Expiration Date 12 months after date of receipt (unopened vial).
  • Alternative Names KEAP1; kelch-like ECH-associated protein 1; INrf2; KIAA0132; KLHL19; MGC10630; MGC1114; MGC20887; MGC4407; MGC9454; cytosolic inhibitor of Nrf2; kelch-like protein 19
  • Uniprot Number Q14145
  • Uniprot Number/Name Q14145 (KEAP1_HUMAN)
  • Scientific Background Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin (PubMed:26599395). Required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta. Required for normal blood vessel development, and for normal development of kidney glomeruli. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers with PDGFA
  • Shipping Temperature 2-8°C (on cold packs)
  • UNSPSC CODE 41116161
  • Regulatory Status For research use only.

    Images, Protocols & SDS

  • Flow cytometry analysis: of paraformaldehyde fixed HeLa cells (blue line), permeabilized with 0.5% Triton. Primary incubation 1hr (10 µg/mL) followed by Alexa Fluor 488 secondary antibody (1 µg/mL). IgG control: Unimmunized goat IgG (black line) followed by Alexa Fluor 488 secondary antibody

    Citations & References