Neurexin-1 (NRXN1), Goat Polyclonal Antibody

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Catalog Number
G-1890

    Product Info

  • Product Name Neurexin-1 (NRXN1), Goat Polyclonal Antibody
  • Product Description google Goat anti-Neurexin-1 (NRXN1) Polyclonal Antibody (Unconjugated), suitable for Pep-ELISA, WB, FC.
  • Alternative Names neurexin 1; DKFZp313P2036; NRXN1; FLJ35941; Hs.22998; KIAA0578; neurexin I; Neurexin I-alpha; Neurexin-1-alpha;
  • Application(s) FC, WB, Pep-ELISA
  • Antibody Host Goat
  • Antibody Type Polyclonal
  • Specificity Reacts with Neurexin 1 from Human. This antibody is expected to recognise all reported isoforms.
  • Species Reactivity Dog (Predicted), Human, Mouse (Predicted), Rat (Predicted)
  • Immunogen Description A synthetic peptide consisting of amino acids, C-KEKQPSSAKSSNKN
  • Conjugate Unconjugated
  • Purity Description Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • Regulatory Status For research use only.

    Specifications

  • Product Description Goat anti-Neurexin-1 (NRXN1) Polyclonal Antibody (Unconjugated), suitable for Pep-ELISA, WB, FC.
  • Application(s) FC, WB, Pep-ELISA
  • Application Details Peptide ELISA (1:128000), Western Blot (0.5-1 µg/mL), Flow Cytometry (10 µg/mL). Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
  • Target Neurexin-1 (NRXN1)
  • Specificity Reacts with Neurexin 1 from Human. This antibody is expected to recognise all reported isoforms.
  • Target Host Species Human
  • Species Reactivity Dog (Predicted), Human, Mouse (Predicted), Rat (Predicted)
  • Antibody Host Goat
  • Antibody Type Polyclonal
  • Antibody Isotype IgG
  • Conjugate Unconjugated
  • Immunogen Description A synthetic peptide consisting of amino acids, C-KEKQPSSAKSSNKN
  • Sequence KEKQPSSAKSSNKN
  • Purity Description Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • Format Liquid antibody. Supplied at 0.5 mg/mL in Tris saline, 0.02% sodium azide, pH 7.3 with 0.5% bovine serum albumin.
  • Storage Instructions Upon receipt, aliquot and store at -20°C long-term. Store at 2-8°C short-term (up to 2 weeks). Minimize freezing and thawing.
  • Batch Number Please see item label.
  • Expiration Date 12 months after date of receipt (unopened vial).
  • Alternative Names neurexin 1; DKFZp313P2036; NRXN1; FLJ35941; Hs.22998; KIAA0578; neurexin I; Neurexin I-alpha; Neurexin-1-alpha;
  • Uniprot Number Q9ULB1
  • Uniprot Number/Name Q9ULB1 (NRX1A_HUMAN)
  • Scientific Background Cell surface protein involved in cell-cell-interactions, exocytosis of secretory granules and regulation of signal transmission. Function is isoform-specific. Alpha-type isoforms have a long N-terminus with six laminin G-like domains and play an important role in synaptic signal transmission. Alpha-type isoforms play a role in the regulation of calcium channel activity and Ca2+-triggered neurotransmitter release at synapses and at neuromuscular junctions. They play an important role in Ca2+-triggered exocytosis of secretory granules in pituitary gland (Uniprot).
  • Shipping Temperature 2-8°C (on cold packs)
  • UNSPSC CODE 41116161
  • Regulatory Status For research use only.

    Images, Protocols & SDS

  • A. Western Blot: HEK293 lysate (10 ug protein in RIPA buffer) overexpressing Human NRXN1 with DYKDDDDK tag probed with G-1890-100 (0.5 µg/mL) in Lane A and probed with anti- DYKDDDDK Tag (1/3000) in lane C. Mock-transfected HEK293 probed with G-1890-100 (1 mg/mL) in Lane B. Detected by chemiluminescence. B. Flow cytometry analysis: of paraformaldehyde fixed Kelly cells (blue line), permeabilized with 0.5% Triton. Primary incubation 1hr (10 µg/mL) followed by Alexa Fluor 488 secondary antibody (1 µg/mL). IgG control: Unimmunized goat IgG (black line) followed by Alexa Fluor 488 secondary antibody.

    Citations & References