Product NameNeuronal migration protein doublecortin (DCX), Goat Polyclonal Antibody
Product DescriptiongoogleGoat anti-Neuronal migration protein doublecortin (DCX) Polyclonal Antibody (Unconjugated), suitable for Pep-ELISA, ICC, FC.
Alternative NamesDCX; doublecortin; RP5-914P14.1; DBCN; DC; FLJ51296; LISX; SCLH; XLIS; OTTHUMP00000023860; OTTHUMP00000216316; doublecortex; doublin; lis-X; lissencephalin-X; neuronal migration protein doublecortin
Application(s)FC, ICC, Pep-ELISA
Antibody HostGoat
Antibody TypePolyclonal
SpecificityReacts with Doublecortin / DCX (aa69-81) from Human. This antibody is expected to recognize reported isoform a (NP_000546.2) only.
Species ReactivityBovine, Human, Mouse
Immunogen DescriptionA synthetic peptide consisting of amino acids, DRSHCQSLRFHQN
ConjugateUnconjugated
Purity DescriptionPurified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Product DescriptionGoat anti-Neuronal migration protein doublecortin (DCX) Polyclonal Antibody (Unconjugated), suitable for Pep-ELISA, ICC, FC.
Application(s)FC, ICC, Pep-ELISA
Application DetailsPeptide ELISA (1:26,000), Immunocytochemistry (10 µg/mL), Flow Cytometry (10 µg/mL). Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
TargetNeuronal migration protein doublecortin (DCX)
SpecificityReacts with Doublecortin / DCX (aa69-81) from Human. This antibody is expected to recognize reported isoform a (NP_000546.2) only.
Target Host SpeciesHuman
Species ReactivityBovine, Human, Mouse
Antibody HostGoat
Antibody TypePolyclonal
Antibody IsotypeIgG
ConjugateUnconjugated
Immunogen DescriptionA synthetic peptide consisting of amino acids, DRSHCQSLRFHQN
SequenceDRSHCQSLRFHQN
Purity DescriptionPurified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
FormatLiquid antibody. Supplied at 0.5 mg/mL in Tris saline, 0.02% sodium azide, pH 7.3 with 0.5% bovine serum albumin.
Storage InstructionsUpon receipt, aliquot and store at -20°C long-term. Store at 2-8°C short-term (up to 2 weeks). Minimize freezing and thawing.
Batch NumberPlease see item label.
Expiration Date12 months after date of receipt (unopened vial).
Alternative NamesDCX; doublecortin; RP5-914P14.1; DBCN; DC; FLJ51296; LISX; SCLH; XLIS; OTTHUMP00000023860; OTTHUMP00000216316; doublecortex; doublin; lis-X; lissencephalin-X; neuronal migration protein doublecortin
Scientific BackgroundMicrotubule-associated protein required for initial steps of neuronal dispersion and cortex lamination during cerebral cortex development. May act by competing with the putative neuronal protein kinase DCLK1 in binding to a target protein. May in that way participate in a signaling pathway that is crucial for neuronal interaction before and during migration, possibly as part of a calcium ion-dependent signal transduction pathway. May be part with PAFAH1B1/LIS-1 of overlapping, but distinct, signaling pathways that promote neuronal migration.