Sodium-dependent serotonin transporter (SERT), Goat Polyclonal Antibody

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Catalog Number
G-1905

    Product Info

  • Product Name Sodium-dependent serotonin transporter (SERT), Goat Polyclonal Antibody
  • Product Description google Goat anti-Sodium-dependent serotonin transporter (SERT) Polyclonal Antibody (Unconjugated), suitable for Pep-ELISA, ICC, FC.
  • Alternative Names SLC6A4; solute carrier family 6 (neurotransmitter transporter, serotonin), member 4; 5-HTT; 5-HTTLPR; 5HTT; HTT; OCD1; SERT; hSERT; 5-hydroxytryptamine transporter; 5HT transporter; Na+/Cl- dependent serotonin transporter; OTTHUMP00000163632; OTTHUMP00000163633; sodium-dependent serotonin transporter; solute carrier family 6 member 4
  • Application(s) FC, ICC, Pep-ELISA
  • Antibody Host Goat
  • Antibody Type Polyclonal
  • Specificity Reacts with SLC6A4 (aa605-618) from Human.
  • Species Reactivity Bovine, Human, Mouse, Rat
  • Immunogen Description A synthetic peptide consisting of amino acids, C-KERIIKSITPETPT
  • Conjugate Unconjugated
  • Purity Description Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • Regulatory Status For research use only.

    Specifications

  • Product Description Goat anti-Sodium-dependent serotonin transporter (SERT) Polyclonal Antibody (Unconjugated), suitable for Pep-ELISA, ICC, FC.
  • Application(s) FC, ICC, Pep-ELISA
  • Application Details Peptide ELISA (1:32000), Immunocytochemistry (10 µg/mL), Flow Cytometry (10 µg/mL). Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
  • Target Sodium-dependent serotonin transporter (SERT)
  • Specificity Reacts with SLC6A4 (aa605-618) from Human.
  • Target Host Species Human
  • Species Reactivity Bovine, Human, Mouse, Rat
  • Antibody Host Goat
  • Antibody Type Polyclonal
  • Antibody Isotype IgG
  • Conjugate Unconjugated
  • Immunogen Description A synthetic peptide consisting of amino acids, C-KERIIKSITPETPT
  • Sequence KERIIKSITPETPT
  • Purity Description Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • Format Liquid antibody. Supplied at 0.5 mg/mL in Tris saline, 0.02% sodium azide, pH 7.3 with 0.5% bovine serum albumin.
  • Storage Instructions Upon receipt, aliquot and store at -20°C long-term. Store at 2-8°C short-term (up to 2 weeks). Minimize freezing and thawing.
  • Batch Number Please see item label.
  • Expiration Date 12 months after date of receipt (unopened vial).
  • Alternative Names SLC6A4; solute carrier family 6 (neurotransmitter transporter, serotonin), member 4; 5-HTT; 5-HTTLPR; 5HTT; HTT; OCD1; SERT; hSERT; 5-hydroxytryptamine transporter; 5HT transporter; Na+/Cl- dependent serotonin transporter; OTTHUMP00000163632; OTTHUMP00000163633; sodium-dependent serotonin transporter; solute carrier family 6 member 4
  • Uniprot Number P31645
  • Uniprot Number/Name P31645 (SC6A4_HUMAN)
  • Scientific Background Serotonin transporter whose primary function in the central nervous system involves the regulation of serotonergic signaling via transport of serotonin molecules from the synaptic cleft back into the pre-synaptic terminal for re-utilization. Plays a key role in mediating regulation of the availability of serotonin to other receptors of serotonergic systems. Terminates the action of serotonin and recycles it in a sodium-dependent manner.
  • Shipping Temperature 2-8°C (on cold packs)
  • UNSPSC CODE 41116161
  • Regulatory Status For research use only.

    Images, Protocols & SDS

  • A. Immunofluorescence analysis: of paraformaldehyde fixed HepG2 cells, permeabilized with 0.15% Triton. Primary incubation 1hr (10 µg/mL) followed by Alexa Fluor 488 secondary antibody (2 µg/mL), showing Golgi apparatus/vesicle staining. The nuclear stain is DAPI (blue). Negative control: Unimmunized goat IgG (10 µg/mL) followed by Alexa Fluor 488 secondary antibody (2 µg/mL). B. Flow cytometry analysis: of paraformaldehyde fixed Jurkat cells (blue line), permeabilized with 0.5% Triton. Primary incubation 1hr (10 µg/mL) followed by Alexa Fluor 488 secondary antibody (2 µg/mL). IgG control: Unimmunized goat IgG (black line) followed by Alexa Fluor 488 secondary antibody.

    Citations & References