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Histamine H3 receptor (HH3R), Rabbit Polyclonal Antibody
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Catalog Number
R-1063
- Product Name Histamine H3 receptor (HH3R), Rabbit Polyclonal Antibody
- Product Description Rabbit anti-Histamine H3 receptor (HH3R) Polyclonal Antibody (Unconjugated), suitable for WB.
- Alternative Names HH3R; G-protein coupled receptor 97; HRH3; GPCR97;
- Application(s) WB
- Antibody Host Rabbit
- Antibody Type Polyclonal
- Specificity The specificity of this antibody has been confirmed by WB against the antigen. Human; Rat; Predicted to react with mouse due to sequence homology.
- Species Reactivity Human, Mouse (Predicted), Rat
- Immunogen Description A synthetic peptide (CPQKLKIQPHSSLEHCWK) corresponding to a region (428-445) from the C-terminus of human Histamine H3 receptor. To enhance the immunological response, this peptide was coupled to carrier protein BSA.
- Conjugate Unconjugated
- Purity Description Affinity purified on antigen column
- Regulatory Status For research use only.
Product Info
- Product Description Rabbit anti-Histamine H3 receptor (HH3R) Polyclonal Antibody (Unconjugated), suitable for WB.
- Application(s) WB
- Application Details Western Blotting (WB). A concentration of 0.75 µg/mL is recommended for WB. Human Histamine H3 receptor (isoform 1) has a predicted length of 445 residues and MW of 49 kDa. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
- Target Histamine H3 receptor (HH3R)
- Specificity The specificity of this antibody has been confirmed by WB against the antigen. Human; Rat; Predicted to react with mouse due to sequence homology.
- Target Host Species Human
- Species Reactivity Human, Mouse (Predicted), Rat
- Antibody Host Rabbit
- Antibody Type Polyclonal
- Antibody Isotype IgG
- Conjugate Unconjugated
- Immunogen Description A synthetic peptide (CPQKLKIQPHSSLEHCWK) corresponding to a region (428-445) from the C-terminus of human Histamine H3 receptor. To enhance the immunological response, this peptide was coupled to carrier protein BSA.
- Purity Description Affinity purified on antigen column
- Format Lyophilized with 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3
- Reconstitution Instructions Spin vial briefly before opening. Reconstitute in 100 µL sterile-filtered, ultrapure water to achieve an antibody concentration of 1 mg/mL. Centrifuge to remove any insoluble material.
- Storage Instructions At least 12 months after purchase at 2-8°C (lyophilized formulations). After reconstitution, aliquot and store at -20°C for a higher stability. Avoid freeze-thaw cycles
- Batch Number Please see item label.
- Expiration Date 12 months after date of receipt (unopened vial).
- Alternative Names HH3R; G-protein coupled receptor 97; HRH3; GPCR97;
- Uniprot Number Q9Y5N1
- Uniprot Number/Name Q9Y5N1 (HRH3_HUMAN)
- Scientific Background The Histamine H3 receptor is a multi-pass membrane protein that belongs to the G-protein coupled receptor 1 family. This protein is primarily expressed in the CNS. At least 7 isoforms are produced by alternative splicing. Expression of these isoforms varies with isoform 3 and isoform 7 being highly expressed in the thalamus, caudate nucleus and cerebellum while isoforms 5 and 6 show a poor expression. Isoform 5 and isoform 6 show a high expression in the amygdala, substantia nigra, cerebral cortex and hypothalamus. Isoform 7 is not found in hypothalamus or substantia nigra.
- Shipping Temperature 25°C (ambient)
- UNSPSC CODE 41116161
- Regulatory Status For research use only.