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T-cell surface glycoprotein CD4, Mouse Monoclonal Antibody
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Catalog Number
M-1165
- Product Name T-cell surface glycoprotein CD4, Mouse Monoclonal Antibody
- Product Description Mouse anti-T-cell surface glycoprotein CD4 Monoclonal Antibody (Unconjugated), suitable for IHC-Frozen, IHC-Paraffin-embedded.
- Alternative Names T-cell surface glycoprotein CD4; T-cell surface antigen T4/Leu-3; W3/25 antigen; CD4mut;
- Application(s) IHC-Frozen, IHC-Paraffin-embedded
- Antibody Host Mouse
- Antibody Type Monoclonal
- Specificity The specificity of this antibody has been confirmed by immunohistochemistry against the antigen. Human; rat;
- Species Reactivity Human, Rat
- Immunogen Description CD4 transfected mouse T-cell hybridoma 3DT followed by CD4+ human T-cell CEM cell line
- Conjugate Unconjugated
- Purity Description IgG
- Regulatory Status For research use only.
Product Info
- Product Description Mouse anti-T-cell surface glycoprotein CD4 Monoclonal Antibody (Unconjugated), suitable for IHC-Frozen, IHC-Paraffin-embedded.
- Application(s) IHC-Frozen, IHC-Paraffin-embedded
- Application Details Immunohistochemistry (IHC-Frozen). A concentration of 1.0 µg/mL is recommended to detect CD4 in formalin/acetone fixed tissues. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
- Target T-cell surface glycoprotein CD4
- Specificity The specificity of this antibody has been confirmed by immunohistochemistry against the antigen. Human; rat;
- Target Host Species Human
- Species Reactivity Human, Rat
- Antibody Host Mouse
- Antibody Type Monoclonal
- Antibody Isotype IgG
- Clone Name CA-4
- Conjugate Unconjugated
- Immunogen Description CD4 transfected mouse T-cell hybridoma 3DT followed by CD4+ human T-cell CEM cell line
- Purity Description IgG
- Format Liquid (0.5 mL). 50% glycerol, 0.9 mg NaCl and 0.2 mg Na2HPO4
- Reconstitution Instructions The liquid formulation should be diluted in PBS (pH 7.4)
- Storage Instructions After reconstitution, aliquot and store at -20°C for a higher stability. Avoid freeze-thaw cycles.
- Batch Number Please see item label.
- Expiration Date 12 months after date of receipt (unopened vial).
- Alternative Names T-cell surface glycoprotein CD4; T-cell surface antigen T4/Leu-3; W3/25 antigen; CD4mut;
- Uniprot Number P01730
- Uniprot Number/Name P01730 (CD4_HUMAN)
- Scientific Background CD4 is a single-pass type I membrane protein expressed on the surface of T helper/inducer cells, regulatory T cells, monocytes, macrophages, dendritic cells and microglia.
- Shipping Temperature 2-8°C (on cold packs)
- UNSPSC CODE 41116161
- Regulatory Status For research use only.
Specifications
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General References
Almolda B. et al. CD4 microglial expression correlates with spontaneous clinical improvement in the acute Lewis rat EAE model. J Neuroimmunol. 2009 Apr 30;209(1-2):65-80.
Jordan C.A. et al. Infection of brain microglial cells by human immunodeficiency virus type 1 is CD4 dependent. J Virol. 1991 Feb;65(2):736-42.