Application DetailsThis antibody is recommended for IHC, and sandwich ELISA. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
TargetGrowth/differentiation factor 11 (GDF-11)
SpecificitySpecificity has been confirmed by direct ELISA against the antigen. Human. Other species have not been tested.
Target Host SpeciesHuman
Species ReactivityHuman
Antibody HostMouse
Antibody TypeMonoclonal
Antibody IsotypeIgG
Clone Name3G6
ConjugateUnconjugated
Immunogen DescriptionPartial recombinant human GDF-11 (310-407) with a GST tag.
Purity DescriptionProtein G purified immunoglobulin
FormatLyophilized from PBS pH 7.2
Reconstitution InstructionsSpin vial briefly before opening. Reconstitute in 100 µL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material.
Storage InstructionsAfter reconstitution keep aliquots at -20°C for higher stability or at 2-8°C with an appropriate antibacterial agent. Glycerol (1:1) may be added for additional stability. Avoid repetitive freeze/thaw cycles.
Batch NumberPlease see item label.
Expiration Date12 months after date of receipt (unopened vial).
Alternative NamesGrowth/differentiatiion factor 11; Bone morphogenetic protein 11; GDF11; BMP11
GDF-11 is a secreted signal that acts globally to specify positional identity along the anterior/posterior axis during development. It plays critical roles in patterning both mesodermal and neural tissues and in establishing the skeletal pattern. It exists as a disulfide-linked homodimer. It belongs to the TGF-beta family.
Immunohistochemical detection of GDF-11 on formalin fixed, paraffin-embedded, human pancreas. Anti-GDF-11 primary antibody, catalogue number M-885-100, was used at a concentration of 3 µg/mL.