Product NameActivity-regulated cytoskeleton-associated protein (Arg3.1), Rabbit Polyclonal Antibody
Product DescriptiongoogleRabbit anti-Activity-regulated cytoskeleton-associated protein (Arg3.1) Polyclonal Antibody (Unconjugated), suitable for IHC-Frozen.
Alternative NamesARC; activity regulated cytoskeletal-associated protein; Activity-regulated gene 3.1 protein homolog; Arg3.1; RCA/ARG3.1; ARC;
Application(s)IHC-Frozen
Antibody HostRabbit
Antibody TypePolyclonal
SpecificitySpecific for Arg3.1. Rat and Mouse. Other species not yet tested.
Species ReactivityHuman, Mouse, Rat
Immunogen DescriptionA synthetic peptide from the C terminal of human Arg3.1 protein (ARC protein) conjugated to Blue Carrier Protein. The sequence is homologous with mouse and rat form of Arg3.1.
Product DescriptionRabbit anti-Activity-regulated cytoskeleton-associated protein (Arg3.1) Polyclonal Antibody (Unconjugated), suitable for IHC-Frozen.
Application(s)IHC-Frozen
Application DetailsIHC. A dilution of 1: 50 to 1: 1000 is recommended. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
TargetActivity-regulated cytoskeleton-associated protein (Arg3.1)
SpecificitySpecific for Arg3.1. Rat and Mouse. Other species not yet tested.
Target Host SpeciesHuman
Species ReactivityHuman, Mouse, Rat
Antibody HostRabbit
Antibody TypePolyclonal
Antibody IsotypeMixed
ConjugateUnconjugated
Immunogen DescriptionA synthetic peptide from the C terminal of human Arg3.1 protein (ARC protein) conjugated to Blue Carrier Protein. The sequence is homologous with mouse and rat form of Arg3.1.
Purity DescriptionWhole serum
FormatLyophilized, containing no preservatives
Reconstitution InstructionsSpin vial briefly before opening. Reconstitute in 100 µL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material. Use sterile methods as antibody does not contain preservatives
Storage InstructionsAfter reconstitution keep aliquots at -20°C for a higher stability. Glycerol (1:1) may be added for an additional stability. Sodium azide or other appropriate antibacterial agent should be added if material is to be kept any length of time at 2-8°C. Avoid repetitive freeze/thaw cycles.
Batch NumberPlease see item label.
Expiration Date12 months after date of receipt (unopened vial).
Alternative NamesARC; activity regulated cytoskeletal-associated protein; Activity-regulated gene 3.1 protein homolog; Arg3.1; RCA/ARG3.1; ARC;
Scientific BackgroundArc (also termed activity-regulated cytoskeleton-associated protein or Arg3.1), is an effector immediate early gene whose upregulation has been demonstrated during events of synaptic plasticity. Arg3.1 expression is detectable in neuronal cell bodies and dendrites in the brain regions including striatum and cortex hippocampus, hypothalamus, amygdala.
Immunohistochemical detection of Arg3.1 in free floating cryosectioned rat spinal cord (dorsal horn) using Rabbit antibody to Arg3.1 (ARC): whole serum (R-154-100) at a dilution of 1: 250.
Immunohistochemical detection of Arg3.1 in free floating cryosectioned rat spinal cord (ventral horn) using Rabbit antibody to Arg3.1 (ARC): whole serum (R-154-100) at a dilution of 1: 250.
Immunohistochemical detection of Arg3.1 in free floating cryosectioned rat brain (3d ventricle) using Rabbit antibody to Arg3.1 (ARC): whole serum (R-154-100) at a dilution of 1: 250.
Immunohistochemical detection of Arg3.1 in free floating cryosectioned rat brain (cortex) using Rabbit antibody to Arg3.1 (ARC): whole serum (R-154-100) at a dilution of 1: 250.
Immunohistochemical detection of Arg3.1 in free floating cryosectioned rat brain (cortex) using Rabbit antibody to Arg3.1 (ARC): whole serum (R-154-100) at a dilution of 1: 250.
Immunohistochemical detection of Arg3.1 in free floating cryosectioned rat brain (cortex) using Rabbit antibody to Arg3.1 (ARC): whole serum (R-154-100) at a dilution of 1: 250.
Immunohistochemical detection of Arg3.1 in free floating cryosectioned rat brain (cortex) using Rabbit antibody to Arg3.1 (ARC): whole serum (R-154-100) at a dilution of 1: 250.
Immunohistochemical detection of Arg3.1 in free floating cryosectioned rat brain (3d ventricle) using Rabbit antibody to Arg3.1 (ARC): whole serum (R-154-100) at a dilution of 1: 250.
General ReferencesKajiya K, et al. J. Neurosci. 21:6018-6025(2001). Young J.M, et al. Genome Biol. 4:RESEARCH71.1-RESEARCH71.13(2003). Zhang X., Firestein S. Nat. Neurosci. 5:124-133(2002). Young J.M, et al. Hum. Mol. Genet. 11:535-546(2002). Kelly MP, et al. Neuroscience. 110(4):617-26 (2002).