1800 605-5127
+61 (0)8 8352 7711
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 (APPL1), Rabbit Polyclonal Antibody
As low as
US$327.00
Only %1 left
Catalog Number
R-1331
- Product Name Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 (APPL1), Rabbit Polyclonal Antibody
- Product Description Rabbit anti-Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 (APPL1) Polyclonal Antibody (Unconjugated), suitable for WB, ICC.
- Alternative Names DCC-interacting protein 13-alpha; Dip13-alpha; Adapter protein containing PH domain; PTB domain and leucine zipper motif 1; APPL1; APPL; DIP13A; KIAA1428;
- Application(s) ICC, WB
- Antibody Host Rabbit
- Antibody Type Polyclonal
- Specificity This antiserum is known to recognise both mouse and human APPL1.
- Species Reactivity Human, Mouse
- Immunogen Description The C-terminus of Human APPL1 protein (amino acids: 455-709) conjugated to GST.
- Conjugate Unconjugated
- Purity Description Whole serum
- Regulatory Status For research use only.
Product Info
- Product Description Rabbit anti-Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 (APPL1) Polyclonal Antibody (Unconjugated), suitable for WB, ICC.
- Application(s) ICC, WB
- Application Details Western Blotting (WB) and Immunoprecipitation (IP). A dilution of 1:1,000 is recommended for WB. A concentration of 3 µL/reaction is recommended for IP. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
- Target Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 (APPL1)
- Specificity This antiserum is known to recognise both mouse and human APPL1.
- Target Host Species Human
- Species Reactivity Human, Mouse
- Antibody Host Rabbit
- Antibody Type Polyclonal
- Antibody Isotype Mixed
- Conjugate Unconjugated
- Immunogen Description The C-terminus of Human APPL1 protein (amino acids: 455-709) conjugated to GST.
- Purity Description Whole serum
- Format Lyophilized
- Reconstitution Instructions Spin vial briefly before opening. Reconstitute in 100 µL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material.
- Storage Instructions At least 12 months after purchase at 2-8°C (lyophilized formulations). After reconstitution, aliquot and store at -20°C for a higher stability. Avoid freeze-thaw cycles.
- Batch Number Please see item label.
- Expiration Date 12 months after date of receipt (unopened vial).
- Alternative Names DCC-interacting protein 13-alpha; Dip13-alpha; Adapter protein containing PH domain; PTB domain and leucine zipper motif 1; APPL1; APPL; DIP13A; KIAA1428;
- Uniprot Number Q9UKG1
- Uniprot Number/Name Q9UKG1 (DP13A_HUMAN)
- Scientific Background APPL1 (adaptor protein containing PH domain, PTB domain and leucine zipper motif 1) mediates adiponectin signaling in various types of cells. APPL1 is also thought to have a role in insulin signaling.
- Shipping Temperature 25°C (ambient)
- UNSPSC CODE 41116161
- Regulatory Status For research use only.
Specifications
-
General References
Mao X. et al (2006) APPL1 binds to adiponectin receptors and mediates adiponectin signalling and function Nat Cell Biol. 2006 May;8(5):516-23.
Wang C. et al (2009) Yin-Yang regulation of adiponectin signaling by APPL isoforms in muscle cells J Biol Chem. 2009 Nov 13;284(46):31608-15.
Zhou L. et al (2009) Adiponectin activates AMP-activated protein kinase in muscle cells via APPL1/LKB1-dependent and phospholipase C/Ca2+/Ca2+/calmodulin-dependent protein kinase kinase-dependent pathways J Biol Chem. 2009 Aug 14;284(33):22426-35