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Growth Hormone receptor (GH receptor), Rabbit Polyclonal Antibody
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Catalog Number
R-1112
Discontinued
- Product Name Growth Hormone receptor (GH receptor), Rabbit Polyclonal Antibody
- Product Description Rabbit anti-Growth Hormone receptor (GH receptor) Polyclonal Antibody (Unconjugated), suitable for WB, IHC-Frozen, IHC-Paraffin-embedded.
- Alternative Names GHR; GH receptor; Somatotropin receptor;
- Application(s) IHC-Frozen, IHC-Paraffin-embedded, WB
- Antibody Host Rabbit
- Antibody Type Polyclonal
- Specificity The specificity of this antibody has been confirmed by WB and IHC against the antigen. Human; rat; predicted to react with mouse due to sequence homology;
- Species Reactivity Human, Mouse (Predicted), Rat
- Immunogen Description A synthetic peptide (CPDYVSAGENSCYFNSS) corresponding to a region (101-117) from human Growth Hormone receptor. To enhance the immunological response, this peptide was coupled to carrier protein BSA.
- Conjugate Unconjugated
- Purity Description Affinity purified on antigen column
- Regulatory Status For research use only.
Product Info
- Product Description Rabbit anti-Growth Hormone receptor (GH receptor) Polyclonal Antibody (Unconjugated), suitable for WB, IHC-Frozen, IHC-Paraffin-embedded.
- Application(s) IHC-Frozen, IHC-Paraffin-embedded, WB
- Application Details Immunohistochemistry (IHC) and Western Blotting (WB). A concentration of 0.75 µg/mL is recommended for WB. Human Growth Hormone receptor (isoform GHRfl) has a predicted length of 638 residues and MW of 72 kDa. A concentration of 1.0-2.0 µg/mL is recommended to detect the protein in formalin fixed and paraffin embedded tissues. Antigen retrieval is required. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
- Target Growth Hormone receptor (GH receptor)
- Specificity The specificity of this antibody has been confirmed by WB and IHC against the antigen. Human; rat; predicted to react with mouse due to sequence homology;
- Target Host Species Human
- Species Reactivity Human, Mouse (Predicted), Rat
- Antibody Host Rabbit
- Antibody Type Polyclonal
- Antibody Isotype IgG
- Conjugate Unconjugated
- Immunogen Description A synthetic peptide (CPDYVSAGENSCYFNSS) corresponding to a region (101-117) from human Growth Hormone receptor. To enhance the immunological response, this peptide was coupled to carrier protein BSA.
- Purity Description Affinity purified on antigen column
- Format Lyophilized with 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3
- Reconstitution Instructions Spin vial briefly before opening. Reconstitute in 100 µL sterile-filtered, ultrapure water to achieve an antibody concentration of 1 mg/mL. Centrifuge to remove any insoluble material.
- Storage Instructions At least 12 months after purchase at 2-8°C (lyophilized formulations). After reconstitution, aliquot and store at -20°C for a higher stability.Avoid freeze-thaw cycles
- Batch Number Please see item label.
- Expiration Date 12 months after date of receipt (unopened vial).
- Alternative Names GHR; GH receptor; Somatotropin receptor;
- Uniprot Number P10912
- Uniprot Number/Name P10912 (GHR_HUMAN)
- Scientific Background Growth Hormone receptor (GRH) is a single-pass type I membrane protein and a receptor for pituitary gland growth hormone. The binding of growth hormone to the receptor leads to the dimerization of the receptor and the activation of signal transduction pathways leading to growth. At least 4 isoforms are produced by alternative splicing.
- Shipping Temperature 25°C (ambient)
- UNSPSC CODE 41116161
- Regulatory Status For research use only.