Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 (APPL2), Rabbit Polyclonal Antibody

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Catalog Number
R-1332

    Product Info

  • Product Name Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 (APPL2), Rabbit Polyclonal Antibody
  • Product Description google Rabbit anti-Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 (APPL2) Polyclonal Antibody (Unconjugated), suitable for WB, ICC.
  • Alternative Names DCC-interacting protein 13-beta; Dip13-beta; Adapter protein containing PH domain; PTB domain and leucine zipper motif 2; APPL2; DIP13B;
  • Application(s) ICC, WB
  • Antibody Host Rabbit
  • Antibody Type Polyclonal
  • Specificity This antiserum is known to recognise both mouse and human APPL2.
  • Species Reactivity Human, Mouse
  • Immunogen Description Mouse APPL2 protein (amino acids: 619-662) conjugated to GST.
  • Conjugate Unconjugated
  • Purity Description Whole serum
  • Regulatory Status For research use only.

    Specifications

  • Product Description Rabbit anti-Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 (APPL2) Polyclonal Antibody (Unconjugated), suitable for WB, ICC.
  • Application(s) ICC, WB
  • Application Details Western Blotting (WB) and Immunoprecipitation (IP). A dilution between 1:2500 and 1:5000 is recommended for WB. A concentration of 3 µL/reaction is recommended for IP. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
  • Target Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 (APPL2)
  • Specificity This antiserum is known to recognise both mouse and human APPL2.
  • Target Host Species Mouse
  • Species Reactivity Human, Mouse
  • Antibody Host Rabbit
  • Antibody Type Polyclonal
  • Antibody Isotype Mixed
  • Conjugate Unconjugated
  • Immunogen Description Mouse APPL2 protein (amino acids: 619-662) conjugated to GST.
  • Purity Description Whole serum
  • Format Liquid. 15% glycerol
  • Storage Instructions Aliquot and store at -20°C for a higher stability. Avoid freeze-thaw cycles.
  • Batch Number Please see item label.
  • Expiration Date 12 months after date of receipt (unopened vial).
  • Alternative Names DCC-interacting protein 13-beta; Dip13-beta; Adapter protein containing PH domain; PTB domain and leucine zipper motif 2; APPL2; DIP13B;
  • Uniprot Number Q8NEU8
  • Uniprot Number/Name Q8NEU8 (DP13B_HUMAN)
  • Scientific Background APPL2 is an isoform of APPL1 with 54% identity in their protein sequences. APPL2 has a role in cell proliferation and embryonic development. Recently, it was shown that APPL2 regulates FSH signaling and acts as a negative regulator in adiponectin signaling.
  • Shipping Temperature 2-8°C (on cold packs)
  • UNSPSC CODE 41116161
  • Regulatory Status For research use only.

    Images, Protocols & SDS

  • Western blot analysis with Rabbit polyclonal antibody to mouse APPL2, catalog number R-1332-100. Tissue homogenates of mouse brain (B), liver (Li), muscle (M), fat (F), heart (H), kidney (K), spleen (S) and pancreas (P) were used and 30 µg of protein was loaded in each lane. Image courtesy of Wang C. et al (2009) J Biol Chem.