SpecificityBinds to p55 chain of IL2R on human T cells, Tac antigen, which is expressed on T cells activated by mitogens, soluble antigens, and alloantigens but not on resting T cells, thymocytes, B cells, monocytes, activated B cells, leukemic T cell blasts from patients with acute lymphoblastic leukemia, and long-term T cell lines.
Species ReactivityHuman, Primate
Immunogen DescriptionCultured T-cells derived from a patient with Mycosis fungoides.
ConjugateUnconjugated
Concentration1 mg/mL
Purity DescriptionPurified antibody, via affinity chromatography
SpecificityBinds to p55 chain of IL2R on human T cells, Tac antigen, which is expressed on T cells activated by mitogens, soluble antigens, and alloantigens but not on resting T cells, thymocytes, B cells, monocytes, activated B cells, leukemic T cell blasts from patients with acute lymphoblastic leukemia, and long-term T cell lines.
Target Host SpeciesHuman
Species ReactivityHuman, Primate
Antibody HostRabbit
Antibody TypeRecombinant
Antibody IsotypeIgG, kappa
Clone NameDaclizumab
ConjugateUnconjugated
Immunogen DescriptionCultured T-cells derived from a patient with Mycosis fungoides.
Purity DescriptionPurified antibody, via affinity chromatography
FormatLiquid. PBS with 0.02% Proclin 300.
Concentration1 mg/mL
Storage InstructionsStore at 2-8°C for up to 1 month. For longer storage, aliquot and store at -20_C. Avoid mulitiple freeze thaw cycles.
Batch NumberPlease see item label.
Expiration DateStore at 2-8⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C for up to 12 months.
Scientific BackgroundThis chimeric rabbit antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Flow-cytometry using the anti-CD25 (IL2R) research biosimilar antibody Daclizumab (R-2030-200) Human lymphocytes were stained with an isotype control (panel A) or the rabbit-chimeric version of Daclizumab (R-2030-200, panel B) at a concentration of 1 µg/mL for 30 mins at RT. After washing, bound antibody was detected using a AF488 conjugated donkey anti-rabbit antibody and cells analysed on a FACSCanto flow-cytometer.