Interleukin-2 receptor subunit alpha (IL-2R), Rabbit Recombinant Antibody

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Catalog Number
R-2030

    Product Info

  • Product Name Interleukin-2 receptor subunit alpha (IL-2R), Rabbit Recombinant Antibody
  • Product Description google Rabbit anti-Interleukin-2 receptor subunit alpha (IL-2R) Recombinant Antibody (Unconjugated), suitable for FC, Block.
  • Alternative Names CD25; Interleukin-2 receptor subunit alpha; IL-2 receptor subunit alpha; IL-2R subunit alpha; IL-2-RA; IL2-RA; TAC antigen; p55
  • Application(s) Block, FC
  • Antibody Host Rabbit
  • Antibody Type Recombinant
  • Specificity Binds to p55 chain of IL2R on human T cells, Tac antigen, which is expressed on T cells activated by mitogens, soluble antigens, and alloantigens but not on resting T cells, thymocytes, B cells, monocytes, activated B cells, leukemic T cell blasts from patients with acute lymphoblastic leukemia, and long-term T cell lines.
  • Species Reactivity Human, Primate
  • Immunogen Description Cultured T-cells derived from a patient with Mycosis fungoides.
  • Conjugate Unconjugated
  • Concentration 1 mg/mL
  • Purity Description Purified antibody, via affinity chromatography
  • Regulatory Status For research use only.

    Specifications

  • Product Description Rabbit anti-Interleukin-2 receptor subunit alpha (IL-2R) Recombinant Antibody (Unconjugated), suitable for FC, Block.
  • Application(s) Block, FC
  • Target Interleukin-2 receptor subunit alpha (IL-2R)
  • Specificity Binds to p55 chain of IL2R on human T cells, Tac antigen, which is expressed on T cells activated by mitogens, soluble antigens, and alloantigens but not on resting T cells, thymocytes, B cells, monocytes, activated B cells, leukemic T cell blasts from patients with acute lymphoblastic leukemia, and long-term T cell lines.
  • Target Host Species Human
  • Species Reactivity Human, Primate
  • Antibody Host Rabbit
  • Antibody Type Recombinant
  • Antibody Isotype IgG, kappa
  • Clone Name Daclizumab
  • Conjugate Unconjugated
  • Immunogen Description Cultured T-cells derived from a patient with Mycosis fungoides.
  • Purity Description Purified antibody, via affinity chromatography
  • Format Liquid. PBS with 0.02% Proclin 300.
  • Concentration 1 mg/mL
  • Storage Instructions Store at 2-8°C for up to 1 month. For longer storage, aliquot and store at -20_C. Avoid mulitiple freeze thaw cycles.
  • Batch Number Please see item label.
  • Expiration Date Store at 2-8⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C for up to 12 months.
  • Alternative Names CD25; Interleukin-2 receptor subunit alpha; IL-2 receptor subunit alpha; IL-2R subunit alpha; IL-2-RA; IL2-RA; TAC antigen; p55
  • Uniprot Number P01589
  • Uniprot Number/Name P01589 (IL2RA_HUMAN)
  • Scientific Background This chimeric rabbit antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.
  • Shipping Temperature 2-8°C (on cold packs)
  • UNSPSC CODE 41116161
  • Regulatory Status For research use only.

    Images, Protocols & SDS

  • Flow-cytometry using the anti-CD25 (IL2R) research biosimilar antibody Daclizumab (R-2030-200) Human lymphocytes were stained with an isotype control (panel A) or the rabbit-chimeric version of Daclizumab (R-2030-200, panel B) at a concentration of 1 µg/mL for 30 mins at RT. After washing, bound antibody was detected using a AF488 conjugated donkey anti-rabbit antibody and cells analysed on a FACSCanto flow-cytometer.

    Citations & References