Application DetailsImmunohistochemistry (IHC) and Western Blotting (WB). A concentration of 0.5-1.0 µg/mL is recommended for WB. Human CEACAM (precursor) has a predicted length of 702 residues and MW of 77 kDa. A concentration of 0.5-2.0 µg/mL is recommended for IHC to detect the protein in formalin fixed and paraffin embedded tissues. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
Scientific BackgroundCarcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) is a cell surface glycoprotein belonging to the immunoglobulin superfamily. CEACAM5 is found in adenocarcinomas of endodermally derived digestive system epithelia and in fetal colon.