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Matrix metalloproteinase-16 (MMP-16), Rabbit Polyclonal Antibody
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Catalog Number
R-1091
- Product Name Matrix metalloproteinase-16 (MMP-16), Rabbit Polyclonal Antibody
- Product Description Rabbit anti-Matrix metalloproteinase-16 (MMP-16) Polyclonal Antibody (Unconjugated), suitable for WB, IHC-Frozen, IHC-Paraffin-embedded.
- Alternative Names MMP-16; EC 3.4.24.; Membrane-type matrix metalloproteinase 3; MT-MMP 3; MTMMP3; Membrane-type-3 matrix metalloproteinase; MT3-MMP; MT3MMP; MMP-X2; MMP16; MMPX2;
- Application(s) IHC-Frozen, IHC-Paraffin-embedded, WB
- Antibody Host Rabbit
- Antibody Type Polyclonal
- Specificity The specificity of this antibody has been confirmed by WB and IHC against the antigen. Human; rat;
- Species Reactivity Human, Rat
- Immunogen Description A synthetic peptide (YTVFQFKRKGTPRHILY) corresponding to a region (582-598) from human Matrix metalloproteinase-16. To enhance the immunological response, this peptide was coupled to carrier protein BSA.
- Conjugate Unconjugated
- Purity Description Affinity purified on antigen column
- Regulatory Status For research use only.
Product Info
- Product Description Rabbit anti-Matrix metalloproteinase-16 (MMP-16) Polyclonal Antibody (Unconjugated), suitable for WB, IHC-Frozen, IHC-Paraffin-embedded.
- Application(s) IHC-Frozen, IHC-Paraffin-embedded, WB
- Application Details Immunohistochemistry (IHC) and Western Blotting (WB). A concentration of 1.0-2.0 µg/mL is recommended for WB. Human MMP16 (isoform Long) has a predicted length of 607 residues and MW of 70 kDa. A concentration of 0.5-1.0 µg/mL is recommended to detect the protein in formalin fixed and paraffin embedded tissues as well as formalin or acetone fixed frozen tissues. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
- Target Matrix metalloproteinase-16 (MMP-16)
- Specificity The specificity of this antibody has been confirmed by WB and IHC against the antigen. Human; rat;
- Target Host Species Human
- Species Reactivity Human, Rat
- Antibody Host Rabbit
- Antibody Type Polyclonal
- Antibody Isotype IgG
- Conjugate Unconjugated
- Immunogen Description A synthetic peptide (YTVFQFKRKGTPRHILY) corresponding to a region (582-598) from human Matrix metalloproteinase-16. To enhance the immunological response, this peptide was coupled to carrier protein BSA.
- Purity Description Affinity purified on antigen column
- Format Lyophilized with 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3
- Reconstitution Instructions Spin vial briefly before opening. Reconstitute in 100 µL sterile-filtered, ultrapure water to achieve an antibody concentration of 1 mg/mL. Centrifuge to remove any insoluble material.
- Storage Instructions At least 12 months after purchase at 2-8°C (lyophilized formulations). After reconstitution, aliquot and store at -20°C for a higher stability.Avoid freeze-thaw cycles
- Batch Number Please see item label.
- Expiration Date 12 months after date of receipt (unopened vial).
- Alternative Names MMP-16; EC 3.4.24.; Membrane-type matrix metalloproteinase 3; MT-MMP 3; MTMMP3; Membrane-type-3 matrix metalloproteinase; MT3-MMP; MT3MMP; MMP-X2; MMP16; MMPX2;
- Uniprot Number P51512
- Uniprot Number/Name P51512 (MMP16_HUMAN)
- Scientific Background The matrix metalloproteinases (MMPs) are a large family of zinc endopeptidases. All MMPs are synthesized as inactive proenzymes. The activation of these proenzymes is a critical step that leads to degradation of extracellular matrix components such as fibronectin and collagen type III. At least 2 isoforms of MMP16 are produced by alternate splicing. The Long isoform is a single-pass type 1 membrane protein. The Short isoform is secreted. Both forms of MMP16 activate MMP2 (progelatinase A) by cleavage.
- Shipping Temperature 25°C (ambient)
- UNSPSC CODE 41116161
- Regulatory Status For research use only.