Metalloproteinase inhibitor 3, Rabbit Polyclonal Antibody

As low as US$427.00
Only %1 left
Catalog Number
R-1106

    Product Info

  • Product Name Metalloproteinase inhibitor 3, Rabbit Polyclonal Antibody
  • Product Description google Rabbit anti-Metalloproteinase inhibitor 3 Polyclonal Antibody (Unconjugated), suitable for WB.
  • Alternative Names Tissue inhibitor of metalloproteinases 3; TIMP-3; MIG-5; TIMP3;
  • Application(s) WB
  • Antibody Host Rabbit
  • Antibody Type Polyclonal
  • Specificity The specificity of this antibody has been confirmed by WB against the antigen. Human;
  • Species Reactivity Human
  • Immunogen Description A synthetic peptide (WAPPDKSIINATDP) corresponding to a region (198-211) from the C-terminus of human Metalloproteinase inhibitor 3. To enhance the immunological response, this peptide was coupled to carrier protein BSA.
  • Conjugate Unconjugated
  • Purity Description Affinity purified on antigen column
  • Regulatory Status For research use only.

    Specifications

  • Product Description Rabbit anti-Metalloproteinase inhibitor 3 Polyclonal Antibody (Unconjugated), suitable for WB.
  • Application(s) WB
  • Application Details Western Blotting (WB). A concentration of 1.0 µg/mL is recommended for WB. Human TIMP3 (precursor) has a predicted length of 211 residues and MW of 24 kDa. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
  • Target Metalloproteinase inhibitor 3
  • Specificity The specificity of this antibody has been confirmed by WB against the antigen. Human;
  • Target Host Species Human
  • Species Reactivity Human
  • Antibody Host Rabbit
  • Antibody Type Polyclonal
  • Antibody Isotype IgG
  • Conjugate Unconjugated
  • Immunogen Description A synthetic peptide (WAPPDKSIINATDP) corresponding to a region (198-211) from the C-terminus of human Metalloproteinase inhibitor 3. To enhance the immunological response, this peptide was coupled to carrier protein BSA.
  • Purity Description Affinity purified on antigen column
  • Format Lyophilized with 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3
  • Reconstitution Instructions Spin vial briefly before opening. Reconstitute in 100 µL sterile-filtered, ultrapure water to achieve an antibody concentration of 1 mg/mL. Centrifuge to remove any insoluble material.
  • Storage Instructions At least 12 months after purchase at 2-8°C (lyophilized formulations). After reconstitution, aliquot and store at -20°C for a higher stability.Avoid freeze-thaw cycles.
  • Batch Number Please see item label.
  • Expiration Date 12 months after date of receipt (unopened vial).
  • Alternative Names Tissue inhibitor of metalloproteinases 3; TIMP-3; MIG-5; TIMP3;
  • Uniprot Number P35625
  • Uniprot Number/Name P35625 (TIMP3_HUMAN
  • Scientific Background The matrix metalloproteinases (MMPs) are a large family of zinc endopeptidases that degrade extracellular matrix components such as fibronectin and collagen type III. The tissue inhibitors of metalloproteinase (TIMPs) complex with these matrix metalloproteinases and irreversibly inactivate them. The TIMP proteins are homologous and are either secreted in soluble form (TIMP1, TIMP2 and TIMP4) or bind to extracellular matrix components (TIMP3). Metalloproteinase inhibitor 3 (TIMP3) is known to inhibit MMP-1, MMP-2, MMP-3, MMP-7, MMP-9, MMP-13, MMP-14 and MMP-15.
  • Shipping Temperature 25°C (ambient)
  • UNSPSC CODE 41116161
  • Regulatory Status For research use only.

    Images, Protocols & SDS

    Citations & References