SpecificityThe specificity of this antibody has been confirmed by WB and IHC against the antigen. Human; predicted to react with rat and mouse due to sequence homology;
Species ReactivityHuman, Mouse (Predicted), Rat (Predicted)
Immunogen DescriptionA synthetic peptide (YTCVATNKLGNTNASITLY) corresponding to a region (294-312) from human Opioid-binding cell adhesion molecule. To enhance the immunological response, this peptide was coupled to carrier protein BSA.
ConjugateUnconjugated
Purity DescriptionAffinity purified on antigen column
Application DetailsImmunohistochemistry (IHC) and Western Blotting (WB). A concentration of 0.1-0.5 µg/mL is recommended for WB. Human Opioid-binding cell adhesion molecule (precursor) has a predicted length of 345 residues and MW of 38 kDa. A concentration of 0.5-1.0 µg/mL is recommended to detect the protein in formalin fixed and paraffin embedded tissues. Heat mediated antigen retrieval is required. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
SpecificityThe specificity of this antibody has been confirmed by WB and IHC against the antigen. Human; predicted to react with rat and mouse due to sequence homology;
Target Host SpeciesHuman
Species ReactivityHuman, Mouse (Predicted), Rat (Predicted)
Antibody HostRabbit
Antibody TypePolyclonal
Antibody IsotypeIgG
ConjugateUnconjugated
Immunogen DescriptionA synthetic peptide (YTCVATNKLGNTNASITLY) corresponding to a region (294-312) from human Opioid-binding cell adhesion molecule. To enhance the immunological response, this peptide was coupled to carrier protein BSA.
Purity DescriptionAffinity purified on antigen column
Reconstitution InstructionsSpin vial briefly before opening. Reconstitute in 100 µL sterile-filtered, ultrapure water to achieve an antibody concentration of 1 mg/mL. Centrifuge to remove any insoluble material.
Storage InstructionsAt least 12 months after purchase at 2-8°C (lyophilized formulations). After reconstitution, aliquot and store at -20°C for a higher stability.Avoid freeze-thaw cycles.
Batch NumberPlease see item label.
Expiration Date12 months after date of receipt (unopened vial).
Alternative NamesOpioid-binding protein/cell adhesion molecule; OPCmL; OBCAM;
Scientific BackgroundOpioid-binding protein cell adhesion molecule (OPCmL) is a member of the IgLON family of immunoglobulins (Ig). OPCmL binds opioids in the presence of acidic lipids. Inactivation and loss of function of OPCmL may play a role in epithelial ovarian cancer.