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Secretogranin-5, Mouse Monoclonal Antibody
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Catalog Number
M-865
- Product Name Secretogranin-5, Mouse Monoclonal Antibody
- Product Description Mouse anti-Secretogranin-5 Monoclonal Antibody (Unconjugated), suitable for WB, ELISA.
- Alternative Names Neuroendocrine protein 7B2; Secretory granule endocrine protein I; Secretogranin V; Pituitary polypeptide; SCG5; SGNE1
- Application(s) ELISA, WB
- Antibody Host Mouse
- Antibody Type Monoclonal
- Specificity Specificity has been confirmed by WB and direct ELISA against the antigen. Human, mouse and rat. Other species have not been tested.
- Species Reactivity Human, Mouse, Rat
- Immunogen Description Partial recombinant human Secretogranin-5 (amino acids 59-160) with a GST tag.
- Conjugate Unconjugated
- Purity Description Protein G purified immunoglobulin
- Regulatory Status For research use only.
Product Info
- Product Description Mouse anti-Secretogranin-5 Monoclonal Antibody (Unconjugated), suitable for WB, ELISA.
- Application(s) ELISA, WB
- Application Details This antibody is recommended for WB and direct ELISA. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
- Target Secretogranin-5
- Specificity Specificity has been confirmed by WB and direct ELISA against the antigen. Human, mouse and rat. Other species have not been tested.
- Target Host Species Human
- Species Reactivity Human, Mouse, Rat
- Antibody Host Mouse
- Antibody Type Monoclonal
- Antibody Isotype IgG
- Clone Name 8G11
- Conjugate Unconjugated
- Immunogen Description Partial recombinant human Secretogranin-5 (amino acids 59-160) with a GST tag.
- Purity Description Protein G purified immunoglobulin
- Format Lyophilized from PBS pH 7.2
- Reconstitution Instructions Spin vial briefly before opening. Reconstitute in 100 µL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material.
- Storage Instructions After reconstitution keep aliquots at -20°C for higher stability or at 2-8°C with an appropriate antibacterial agent. Glycerol (1:1) may be added for additional stability. Avoid repetitive freeze/thaw cycles.
- Batch Number Please see item label.
- Expiration Date 12 months after date of receipt (unopened vial).
- Alternative Names Neuroendocrine protein 7B2; Secretory granule endocrine protein I; Secretogranin V; Pituitary polypeptide; SCG5; SGNE1
- Uniprot Number P05408
- Uniprot Number/Name P05408 (7B2_HUMAN)
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Scientific Background
Secretogranin-5 is an acidic protein of 186 amino aids and has an expression that seems to be restricted to neurons and endocrine cells. In the brain, it is most abundant in the supraoptic and paraventricular nuclei of the hypothalamus. It acts in neuroendocrine cells as a specific chaperone for proprotein convertase-2 (PC2) which is an important endoprotease involved in the processing of neuroendocrine precursors. It binds to inactive proPC2 in the ER and facilitates its movement toward the secretory pathway where proPC2 is proteolytically matured and activated. It also plays a role in regulating pituitary hormone secretion.
- Shipping Temperature 25°C (ambient)
- UNSPSC CODE 41116161
- Regulatory Status For research use only.
