Product DescriptiongoogleMouse anti-Tachykinin-3 Monoclonal Antibody (Unconjugated), suitable for WB, ELISA.
Alternative NamesZNEUROK1; Neurokinin B; TAC3; NKNB
Application(s)ELISA, WB
Antibody HostMouse
Antibody TypeMonoclonal
SpecificitySpecificity has been confirmed by WB and direct ELISA against the antigen. Human. Rat and mouse samples were negative by IHC. Other species have not been tested.
Species ReactivityHuman
Immunogen DescriptionTAC3 (17-121aa) full-length recombinant human Tachykinin protein with GST tag.
ConjugateUnconjugated
Purity DescriptionProtein G purified immunoglobulin
Product DescriptionMouse anti-Tachykinin-3 Monoclonal Antibody (Unconjugated), suitable for WB, ELISA.
Application(s)ELISA, WB
Application DetailsThis antibody is recommended for WB and ELISA. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
TargetTachykinin-3
SpecificitySpecificity has been confirmed by WB and direct ELISA against the antigen. Human. Rat and mouse samples were negative by IHC. Other species have not been tested.
Target Host SpeciesHuman
Species ReactivityHuman
Antibody HostMouse
Antibody TypeMonoclonal
Antibody IsotypeIgG1, kappa
Clone Name2D7
ConjugateUnconjugated
Immunogen DescriptionTAC3 (17-121aa) full-length recombinant human Tachykinin protein with GST tag.
Purity DescriptionProtein G purified immunoglobulin
FormatLyophilized from PBS pH 7.4
Reconstitution InstructionsSpin vial briefly before opening. Reconstitute in 100 µL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material.
Storage InstructionsStore lyophilized antibody at 2-8ºC. After reconstitution keep aliquots at -20°C for higher stability or at 2-8°C with an appropriate antibacterial agent. Glycerol (1:1) may be added for additional stability. Avoid repetitive freeze/thaw cycles.
Batch NumberPlease see item label.
Expiration Date12 months after date of receipt (unopened vial).
Alternative NamesZNEUROK1; Neurokinin B; TAC3; NKNB
Tachykinins are active peptides which excite neurons, evoke behavioural responses, are potent vasodilators and secretagogues, and contract many smooth muscles. Tachykinin-3 is a secreted protein and its expression during pregnancy is confined to the outer syncytiotophoblast of the placenta. Plasma concentrations of Tachykinin-3 are grossly elevated in pregnancy-induced hypertension and pre-eclampsia.
Western blot detection of recombinant GST tagged human Tachykinin-3.
Sandwich ELISA using the anti-Tachykinin-3 antibody as a capture antibody. The detection limit for GST tagged recombinant Tachykinin-3 is 0.1 ng/mL.
Immunohistochemical detection of neurokinin B synthesizing neurons in the human infundibular nucleus using the M-871-100 primary antibody (0.1 µg/mL) to tachykinin-3, followed by its visualization with the biotinylated secondary antibody-ABC method and nickel-diaminobenzidine chromogen. Numerous cell bodies are labeled. Photo courtesy of Dr. Erik Hrabovszky, Hungarian Academy of Sciences, Budapest, Hungary.
Immunohistochemical detection of neurokinin B synthesizing neurons in the human infundibular nucleus using the M-871-100 primary antibody (0.1 µg/mL) to tachykinin-3, followed by its visualization with the biotinylated secondary antibody-ABC method and nickel-diaminobenzidine chromogen. Numerous cell fibers are labeled. Photo courtesy of Dr. Erik Hrabovszky, Hungarian Academy of Sciences, Budapest, Hungary.
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