Glycine receptor subunit alpha-1, Mouse Monoclonal Antibody

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Catalog Number
M-838

    Product Info

  • Product Name Glycine receptor subunit alpha-1, Mouse Monoclonal Antibody
  • Product Description google Mouse anti-Glycine receptor subunit alpha-1 Monoclonal Antibody (Unconjugated), suitable for WB, ELISA.
  • Alternative Names Glycine receptor 48 kDa subunit; Glycine receptor strychnine-binding subunit; GLRA1
  • Application(s) ELISA, WB
  • Antibody Host Mouse
  • Antibody Type Monoclonal
  • Specificity Specificity has been confirmed by WB and direct ELISA against the antigen. Human. Other species have not been tested.
  • Species Reactivity Human
  • Immunogen Description Partial recombinant protein of human glycine receptor subunit alpha-1 (aa 121 to 221) with a GST tag.
  • Conjugate Unconjugated
  • Purity Description Protein G purified immunoglobulin
  • Regulatory Status For research use only.

    Specifications

  • Product Description Mouse anti-Glycine receptor subunit alpha-1 Monoclonal Antibody (Unconjugated), suitable for WB, ELISA.
  • Application(s) ELISA, WB
  • Application Details This antibody is recommended for WB, and sandwich ELISA. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
  • Target Glycine receptor subunit alpha-1
  • Specificity Specificity has been confirmed by WB and direct ELISA against the antigen. Human. Other species have not been tested.
  • Target Host Species Human
  • Species Reactivity Human
  • Antibody Host Mouse
  • Antibody Type Monoclonal
  • Antibody Isotype IgG
  • Clone Name 2E6
  • Conjugate Unconjugated
  • Immunogen Description Partial recombinant protein of human glycine receptor subunit alpha-1 (aa 121 to 221) with a GST tag.
  • Purity Description Protein G purified immunoglobulin
  • Format Lyophilized from PBS pH 7.2
  • Reconstitution Instructions Spin vial briefly before opening. Reconstitute in 100 µL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material.
  • Storage Instructions After reconstitution keep aliquots at -20°C for higher stability or at 2-8°C with an appropriate antibacterial agent. Glycerol (1:1) may be added for additional stability. Avoid repetitive freeze/thaw cycles.
  • Batch Number Please see item label.
  • Expiration Date 12 months after date of receipt (unopened vial).
  • Alternative Names Glycine receptor 48 kDa subunit; Glycine receptor strychnine-binding subunit; GLRA1
  • Uniprot Number P23415
  • Uniprot Number/Name P23415 (GLRA1_HUMAN)
  • Scientific Background
    Glycine receptor is a neurotransmitter-gated ion channel. When bound to its ligand, glycine, chloride conductance is increased and consequently inhibits neuronal firing. It is a pentameric receptor composed of alpha and beta subunits and localises to the cell junction, synapse and postsynaptic cell membrane. Defects in GLRA1 cause startle disease (STHE) which is also known as hereditary hyperekplexia or congenital stiff-person syndrome.
  • Shipping Temperature 25°C (ambient)
  • UNSPSC CODE 41116161
  • Regulatory Status For research use only.

    Images, Protocols & SDS

  • Western blot detection of recombinant GST tagged human glycine receptor subunit alpha-1 using catalogue number M-838-100.

    Citations & References