Phytanoyl-CoA dioxygenase, peroxisomal (PhyH), Mouse Monoclonal Antibody

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Catalog Number
M-914

    Product Info

  • Product Name Phytanoyl-CoA dioxygenase, peroxisomal (PhyH), Mouse Monoclonal Antibody
  • Product Description google Mouse anti-Phytanoyl-CoA dioxygenase, peroxisomal (PhyH) Monoclonal Antibody (Unconjugated), suitable for WB, ELISA.
  • Alternative Names Phytanoyl-CoA dioxygenase peroxisomal; Phytanoyl-CoA alpha-hydroxylase; Phytanic acid oxidase; PHYH; PAHX
  • Application(s) ELISA, WB
  • Antibody Host Mouse
  • Antibody Type Monoclonal
  • Specificity Specificity has been confirmed by WB and ELISA against the antigen. Human. Other species have not been tested.
  • Species Reactivity Human
  • Immunogen Description Recombinant human PhyH [1-338], with a GST tag.
  • Conjugate Unconjugated
  • Purity Description Protein G purified immunoglobulin
  • Regulatory Status For research use only.

    Specifications

  • Product Description Mouse anti-Phytanoyl-CoA dioxygenase, peroxisomal (PhyH) Monoclonal Antibody (Unconjugated), suitable for WB, ELISA.
  • Application(s) ELISA, WB
  • Application Details This antibody is recommended for WB and ELISA. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
  • Target Phytanoyl-CoA dioxygenase, peroxisomal (PhyH)
  • Specificity Specificity has been confirmed by WB and ELISA against the antigen. Human. Other species have not been tested.
  • Target Host Species Human
  • Species Reactivity Human
  • Antibody Host Mouse
  • Antibody Type Monoclonal
  • Antibody Isotype IgG
  • Clone Name 1F2-5B9
  • Conjugate Unconjugated
  • Immunogen Description Recombinant human PhyH [1-338], with a GST tag.
  • Purity Description Protein G purified immunoglobulin
  • Format Lyophilized from PBS pH 7.2
  • Reconstitution Instructions Spin vial briefly before opening. Reconstitute in 100 µL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material.
  • Storage Instructions After reconstitution keep aliquots at -20°C for higher stability or at 2-8°C with an appropriate antibacterial agent. Glycerol (1:1) may be added for additional stability. Avoid repetitive freeze/thaw cycles.
  • Batch Number Please see item label.
  • Expiration Date 12 months after date of receipt (unopened vial).
  • Alternative Names Phytanoyl-CoA dioxygenase peroxisomal; Phytanoyl-CoA alpha-hydroxylase; Phytanic acid oxidase; PHYH; PAHX
  • Uniprot Number O14832
  • Uniprot Number/Name O14832 (PAHX_HUMAN)
  • Scientific Background
    PhyH is a peroxisomal protein that is involved in the alpha-oxidation of 3-methyl branched fatty acids. Specifically, this protein converts phytanoyl-CoA to 2-hydroxyphytanoyl-CoA. It requires iron and ascorbate as cofactors and is expressed in liver, kidney, and T-cells but not in spleen, brain, heart, lung and skeletal muscle. Defects in PhyH are a cause of Refsum disease (RD) and deficient protein activity has been associated with Zellweger syndrome and rhizomelic chondrodysplasia punctata. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
  • Shipping Temperature 25°C (ambient)
  • UNSPSC CODE 41116161
  • Regulatory Status For research use only.

    Images, Protocols & SDS

  • Western blot detection of GST tagged recombinant human PhyH. Note the GST tag alone is 26 kDa.

    Citations & References