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Glial cell-derived neurotrophic factor receptor alpha-3 (GFR alpha-3), Rabbit Polyclonal Antibody
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Catalog Number
R-068
- Product Name Glial cell-derived neurotrophic factor receptor alpha-3 (GFR alpha-3), Rabbit Polyclonal Antibody
- Product Description Rabbit anti-Glial cell-derived neurotrophic factor receptor alpha-3 (GFR alpha-3) Polyclonal Antibody (Unconjugated), suitable for WB, IHC-Frozen.
- Alternative Names GDNF family receptor alpha-3; GFR-alpha-3
- Application(s) IHC-Frozen, WB
- Antibody Host Rabbit
- Antibody Type Polyclonal
- Specificity Western blot analysis indicates a high level of specificity to GFR alpha-3 for this antiserum. This antibody is known to react with rat GFR alpha-2.
- Species Reactivity Mouse, Rat
- Immunogen Description A synthetic peptide (MGLSWSPRPPL) as part of mouse GFR alpha-3 protein (aa: 1-11) conjugated to KLH
- Conjugate Unconjugated
- Purity Description Whole serum
- Regulatory Status For research use only.
Product Info
- Product Description Rabbit anti-Glial cell-derived neurotrophic factor receptor alpha-3 (GFR alpha-3) Polyclonal Antibody (Unconjugated), suitable for WB, IHC-Frozen.
- Application(s) IHC-Frozen, WB
- Application Details IHC, WB. A dilution of 1:500 to 1:1000 is recommended for both applications. This antibody stains nicely large neurons in the rat DRG. Specifically, if you would like to perform WB using rat brain homogenate detecting GFR alpha-3, this is the antibody to be used. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
- Target Glial cell-derived neurotrophic factor receptor alpha-3 (GFR alpha-3)
- Specificity Western blot analysis indicates a high level of specificity to GFR alpha-3 for this antiserum. This antibody is known to react with rat GFR alpha-2.
- Target Host Species Mouse
- Species Reactivity Mouse, Rat
- Antibody Host Rabbit
- Antibody Type Polyclonal
- Antibody Isotype Mixed
- Conjugate Unconjugated
- Immunogen Description A synthetic peptide (MGLSWSPRPPL) as part of mouse GFR alpha-3 protein (aa: 1-11) conjugated to KLH
- Purity Description Whole serum
- Format Lyophilized
- Reconstitution Instructions Spin vial briefly before opening. Reconstitute in 100 µL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material.
- Storage Instructions After reconstitution keep aliquots at -20°C for a higher stability, and at 2-8°C with an appropriate antibacterial agent. Glycerol (1:1) may be added for an additional stability. Avoid repetitive freeze/thaw cycles.
- Batch Number Please see item label.
- Expiration Date 12 months after date of receipt (unopened vial).
- Alternative Names GDNF family receptor alpha-3; GFR-alpha-3
- Uniprot Number O35118
- Uniprot Number/Name O35118 (GFRA3_MOUSE)
- Scientific Background FUNCTION: Receptor for the glial cell line-derived neurotrophic factor, artemin. Mediates the artemin-induced autophosphorylation and activation of the RET receptor tyrosine kinase (By similarity). SUBCELLULAR LOCATION: Cell membrane; lipid-anchor; GPI-anchor (By similarity). SIMILARITY: Belongs to the GDNFR family.
- Shipping Temperature 25°C (ambient)
- UNSPSC CODE 41116161
- Regulatory Status For research use only.
Specifications
- General References Naveilhan et al. (1998) Proc. Natl. Acad. Sci. USA. 95(3): 1295