Cerebral dopamine neurotrophic factor (CDNF), Mouse Monoclonal Antibody

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Catalog Number
M-1676

    Product Info

  • Product Name Cerebral dopamine neurotrophic factor (CDNF), Mouse Monoclonal Antibody
  • Product Description google Mouse anti-Cerebral dopamine neurotrophic factor (CDNF) Monoclonal Antibody (Unconjugated), suitable for WB.
  • Alternative Names ARMETL1
  • Application(s) WB
  • Antibody Host Mouse
  • Antibody Type Monoclonal
  • Specificity CDNF (conserved dopamine neurotrophic factor)
  • Species Reactivity Human
  • Immunogen Description Recombinant human CDNF protein produced using CHO-based cell line. Purified from cell culture supernatant.
  • Conjugate Unconjugated
  • Purity Description Purified by protein G affinity chromatography
  • Regulatory Status For research use only.

    Specifications

  • Product Description Mouse anti-Cerebral dopamine neurotrophic factor (CDNF) Monoclonal Antibody (Unconjugated), suitable for WB.
  • Application(s) WB
  • Application Details Western blot (WB) at a suggested dilution of 1:2,000 - 1:4,000. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
  • Target Cerebral dopamine neurotrophic factor (CDNF)
  • Specificity CDNF (conserved dopamine neurotrophic factor)
  • Target Host Species Human
  • Species Reactivity Human
  • Antibody Host Mouse
  • Antibody Type Monoclonal
  • Antibody Isotype IgG1
  • Conjugate Unconjugated
  • Immunogen Description Recombinant human CDNF protein produced using CHO-based cell line. Purified from cell culture supernatant.
  • Purity Description Purified by protein G affinity chromatography
  • Format PBS pH 7.4, with 0.1% sodium azide.
  • Storage Instructions Store at -20°C or -70°C upon receipt. After opening maintain undiluted in smaller aliquots at -20°C or -70°C for up to 6 months. Avoid multiple freeze-thaw cycles.
  • Batch Number Please see item label.
  • Expiration Date 12 months after date of receipt (unopened vial).
  • Alternative Names ARMETL1
  • Uniprot Number Q49AH0
  • Uniprot Number/Name Q49AH0 (CDNF_HUMAN)
  • Scientific Background CDNF (conserved dopamine neurotrophic factor) is a trophic factor for midbrain dopamine neurons in vivo. It prevents the 6-OHDA- (Lindholm et al. 20007; Voutilainen et al., 2011) and MPTP-induced degeneration (Airavaara et al., 2012) of dopamine neurons in rodent models of Parkinson's disease. When administered after 6-OHDA or MPTP -lesioning it restores the dopaminergic function and prevents degeneration of dopamine neurons in substantia nigra pars compacta.
  • Shipping Temperature 25°C (ambient)
  • UNSPSC CODE 41116161
  • Regulatory Status For research use only.

    Images, Protocols & SDS

  • Western Blot testing of anti-CDNF antibody. Line 1. PageRuler Prestained Protein Ladder (#SM0671 Fermentas); Line 2. Recombinant CDNF expressed into the supernatant of CHO cell culture medium.

    Citations & References