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Conserved dopamine neurotrophic factor (CDNF), Rabbit Polyclonal Antibody
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Catalog Number
R-1674
- Product Name Conserved dopamine neurotrophic factor (CDNF), Rabbit Polyclonal Antibody
- Product Description Rabbit anti-Conserved dopamine neurotrophic factor (CDNF) Polyclonal Antibody (Unconjugated), suitable for WB.
- Alternative Names ARMETL1
- Application(s) WB
- Antibody Host Rabbit
- Antibody Type Polyclonal
- Specificity CDNF (conserved dopamine neurotrophic factor)
- Species Reactivity Human
- Immunogen Description Recombinant human CDNF protein produced using CHO-based cell line. Purified from cell culture supernatant.
- Conjugate Unconjugated
- Purity Description Affinity purified
- Regulatory Status For research use only.
Product Info
- Product Description Rabbit anti-Conserved dopamine neurotrophic factor (CDNF) Polyclonal Antibody (Unconjugated), suitable for WB.
- Application(s) WB
- Application Details Western blot (WB) at a suggested dilution of 1:6,000 - 1:10,000. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
- Target Conserved dopamine neurotrophic factor (CDNF)
- Specificity CDNF (conserved dopamine neurotrophic factor)
- Target Host Species Human
- Species Reactivity Human
- Antibody Host Rabbit
- Antibody Type Polyclonal
- Antibody Isotype IgG
- Conjugate Unconjugated
- Immunogen Description Recombinant human CDNF protein produced using CHO-based cell line. Purified from cell culture supernatant.
- Purity Description Affinity purified
- Format Concentrated ammonium sulphate in PBS pH 7.4 containing no preservatives.
-
Reconstitution Instructions
Store antibody stock solution at +4°C upon receipt. DO NOT FREEZE. This product is an (NH4)2SO4 precipitate. To use, mix well by pipetting or vortexing gently prior use, then withdraw the desired amount of antibody stock solution and dilute into your antibody dilution buffer and use normally.
Alternatively, material can be centrifuged at 10K x g for 5 minutes and the liquid sulfate solution carefully removed. Then precipitated antibody can be resuspended in 0.1M P, 250mM NaCL, pH 7.4 solution. The solution should then be divided into working aliquots and stored at -80°C until used. Prevent multiple freeze thaw cycles of aliquots for best product life. - Storage Instructions Store at 2-8°C upon receipt; Do not freeze. See reconstitution instructions for handling information.
- Batch Number Please see item label.
- Expiration Date 12 months after date of receipt (unopened vial).
- Alternative Names ARMETL1
- Uniprot Number Q49AH0
- Uniprot Number/Name Q49AH0 (CDNF_HUMAN)
- Scientific Background CDNF (conserved dopamine neurotrophic factor) is a trophic factor for midbrain dopamine neurons in vivo. It prevents the 6-OHDA- (Lindholm et al. 20007; Voutilainen et al., 2011) and MPTP-induced degeneration (Airavaara et al., 2012) of dopamine neurons in rodent models of Parkinson's disease. When administered after 6-OHDA or MPTP -lesioning it restores the dopaminergic function and prevents degeneration of dopamine neurons in substantia nigra pars compacta.
- Shipping Temperature 2-8°C (on cold packs)
- UNSPSC CODE 41116161
- Regulatory Status For research use only.
