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Neurotrophin-3 (NT-3), Rabbit Polyclonal Antibody
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Catalog Number
R-1016
- Product Name Neurotrophin-3 (NT-3), Rabbit Polyclonal Antibody
- Product Description Rabbit anti-Neurotrophin-3 (NT-3) Polyclonal Antibody (Unconjugated), suitable for WB, IHC-Frozen, IHC-Paraffin-embedded.
- Alternative Names NT-3; NTF3; Neurotrophin-3; HDNF; Nerve growth factor 2; NGF-2;
- Application(s) IHC-Frozen, IHC-Paraffin-embedded, WB
- Antibody Host Rabbit
- Antibody Type Polyclonal
- Specificity The specificity of this antibody has been confirmed by WB and IHC against the antigen. Human; mouse; rat;
- Species Reactivity Human, Mouse, Rat
- Immunogen Description A synthetic peptide (TVLGEIKTGNSPVKQY) corresponding to amino acid sequence 174-189 from human neurotrophin 3 (NT3).
- Conjugate Unconjugated
- Purity Description Affinity purified on antigen column
- Regulatory Status For research use only.
Product Info
- Product Description Rabbit anti-Neurotrophin-3 (NT-3) Polyclonal Antibody (Unconjugated), suitable for WB, IHC-Frozen, IHC-Paraffin-embedded.
- Application(s) IHC-Frozen, IHC-Paraffin-embedded, WB
- Application Details Immunohistochemistry (IHC) and Western Blotting (WB). A concentration of 0.1-0.5 µg/mL is recommended for WB. Human NT3 has a predicted length of 257 amino acids and MW of 29 kDa. A concentration of 0.5-1.0 µg/mL is recommended to detect NT3 in paraffin embedded tissues. Antigen retrieval by boiling the paraffin / formalin section in 10mM citrate buffer, pH 6.0 for 20 minutes is required. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
- Target Neurotrophin-3 (NT-3)
- Specificity The specificity of this antibody has been confirmed by WB and IHC against the antigen. Human; mouse; rat;
- Target Host Species Human
- Species Reactivity Human, Mouse, Rat
- Antibody Host Rabbit
- Antibody Type Polyclonal
- Antibody Isotype IgG
- Conjugate Unconjugated
- Immunogen Description A synthetic peptide (TVLGEIKTGNSPVKQY) corresponding to amino acid sequence 174-189 from human neurotrophin 3 (NT3).
- Purity Description Affinity purified on antigen column
- Format Lyophilized. Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3.
- Reconstitution Instructions Spin vial briefly before opening. Add 0.2 mL of sterile-filtered, ultrapure water to obtain a concentration of 500 µg/mL. Centrifuge to remove any insoluble material.
- Storage Instructions Maintain lyophilized antibody at 2-8°C. After reconstitution, aliquot and store at -20°C for up to 6 months for a higher stability.Avoid freeze-thaw cycles
- Batch Number Please see item label.
- Expiration Date 12 months after date of receipt (unopened vial).
- Alternative Names NT-3; NTF3; Neurotrophin-3; HDNF; Nerve growth factor 2; NGF-2;
- Uniprot Number P20783
- Uniprot Number/Name P20783 (NTF3_HUMAN)
- Scientific Background NT3 is a member of the neurotrophin family, that controls survival and differentiation of visceral and proprioceptive sensory neurons. NT3 is closely related to both NGF and BDNF. It may be involved in the maintenance of the adult nervous system, and may affect development of neurons in the embryo when it is expressed in human placenta. NT3-deficient mice generated by gene targeting display severe movement defects of the limbs. The mature peptide of this protein is identical in all mammals examined including human, pig, rat and mouse. SUBCELLULAR LOCATION: Secreted protein. TISSUE SPECIFICITY: Brain and peripheral tissues. SIMILARITY: Belongs to the NGF-beta family.
- Shipping Temperature 25°C (ambient)
- UNSPSC CODE 41116161
- Regulatory Status For research use only.
