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Cathepsin L, Mouse Monoclonal Antibody
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Catalog Number
M-971
- Product Name Cathepsin L, Mouse Monoclonal Antibody
- Product Description Mouse anti-Cathepsin L Monoclonal Antibody (Unconjugated), suitable for WB, IHC-Frozen, IHC-Paraffin-embedded.
- Alternative Names MEP; CTSL; CTSL1;
- Application(s) IHC-Frozen, IHC-Paraffin-embedded, WB
- Antibody Host Mouse
- Antibody Type Monoclonal
- Specificity The specificity of this antibody has been confirmed by WB and IHC against the antigen. Human; mouse; rat;
- Species Reactivity Human, Mouse, Rat
- Immunogen Description Procathepsin L isolated from human lung cancer cell line EPLC32M1. The epitope is within the sequence GYGFEST (265-271 in procathepsin L and 169-175 in the mature cathepsin L molecule).
- Conjugate Unconjugated
- Purity Description IgG
- Regulatory Status For research use only.
Product Info
- Product Description Mouse anti-Cathepsin L Monoclonal Antibody (Unconjugated), suitable for WB, IHC-Frozen, IHC-Paraffin-embedded.
- Application(s) IHC-Frozen, IHC-Paraffin-embedded, WB
- Application Details Immunohistochemistry (IHC) and Western Blotting (WB). A concentration of 2.0 µg/mL is recommended for WB. A concentration of 4.0 µg/mL is recommended to detect cathepsin L in formalin/acetone fixed tissues. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
- Target Cathepsin L
- Specificity The specificity of this antibody has been confirmed by WB and IHC against the antigen. Human; mouse; rat;
- Target Host Species Human
- Species Reactivity Human, Mouse, Rat
- Antibody Host Mouse
- Antibody Type Monoclonal
- Antibody Isotype IgG
- Clone Name CP-L14
- Conjugate Unconjugated
- Immunogen Description Procathepsin L isolated from human lung cancer cell line EPLC32M1. The epitope is within the sequence GYGFEST (265-271 in procathepsin L and 169-175 in the mature cathepsin L molecule).
- Purity Description IgG
- Format Lyophilized from 1.2% sodium acetate, 2 mg BSA, 0.01 mg NaN3
- Reconstitution Instructions Spin vial briefly before opening. Reconstitute in 1 mL of sterile-filtered PBS (pH 7.4) to achieve an antibody concentration of 100 µg/mL. Centrifuge to remove any insoluble material.
- Storage Instructions At least 12 months after purchase at 2-8°C (lyophilized formulations). After reconstitution, aliquot and store at -20°C for a higher stability. Avoid freeze-thaw cycles.
- Batch Number Please see item label.
- Expiration Date 12 months after date of receipt (unopened vial).
- Alternative Names MEP; CTSL; CTSL1;
- Uniprot Number P07711
- Uniprot Number/Name P07711 (CATL1_HUMAN)
- Scientific Background Cathepsin L is a cystein protease. It is important for the overall degradation of proteins in lysosomes. Cathepsin L substrates include collagen, elastin and alpha 1 protease inhibitor. The protein is initially expressed as procathepsin L (42 kDa) and is proteolytically processed into 30 kDa and 21 kDa forms. This antibody recognises both precursor and mature forms.
- Shipping Temperature 25°C (ambient)
- UNSPSC CODE 41116161
- Regulatory Status For research use only.