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Methyl-CpG-binding protein 2 (MeCP2), Mouse Monoclonal Antibody
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Catalog Number
M-809
- Product Name Methyl-CpG-binding protein 2 (MeCP2), Mouse Monoclonal Antibody
- Product Description Mouse anti-Methyl-CpG-binding protein 2 (MeCP2) Monoclonal Antibody (Unconjugated), suitable for WB, ELISA.
- Alternative Names Voltage-dependent L-type calcium channel subunit beta-2; calcium channel voltage-dependent subunit beta 2; Lambert-Eaton myasthenic syndrome antigen B; MYSB; CACNB2
- Application(s) ELISA, WB
- Antibody Host Mouse
- Antibody Type Monoclonal
- Specificity The specificity of this antibody was confirmed by WB and ELISA against the recombinant GST tagged CAB2 protein. GST tag alone was used as a negative control. This antibody cross reacts with human, mouse and rat CAB2 proteins. Other species have not been tested.
- Species Reactivity Human, Mouse, Rat
- Immunogen Description This antibody was raised against a partial recombinant protein of human CAB2 (amino acids 213 to 301) with a GST tag.
- Conjugate Unconjugated
- Purity Description Protein G purified immunoglobulin
- Regulatory Status For research use only.
Product Info
- Product Description Mouse anti-Methyl-CpG-binding protein 2 (MeCP2) Monoclonal Antibody (Unconjugated), suitable for WB, ELISA.
- Application(s) ELISA, WB
- Application Details This antibody is recommended for WB, direct and sandwich ELISA. The detection limit for recombinant CAB2 protein with GST tag is 0.1ng/mL when this antibody is used in sandwich ELISA. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
- Target Methyl-CpG-binding protein 2 (MeCP2)
- Specificity The specificity of this antibody was confirmed by WB and ELISA against the recombinant GST tagged CAB2 protein. GST tag alone was used as a negative control. This antibody cross reacts with human, mouse and rat CAB2 proteins. Other species have not been tested.
- Target Host Species Human
- Species Reactivity Human, Mouse, Rat
- Antibody Host Mouse
- Antibody Type Monoclonal
- Antibody Isotype IgG
- Clone Name 6C1
- Conjugate Unconjugated
- Immunogen Description This antibody was raised against a partial recombinant protein of human CAB2 (amino acids 213 to 301) with a GST tag.
- Purity Description Protein G purified immunoglobulin
- Format Lyophilized from PBS pH 7.2
- Reconstitution Instructions Spin vial briefly before opening. Reconstitute in 100 µL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material.
- Storage Instructions After reconstitution keep aliquots at -20°C for higher stability or at 2-8°C with an appropriate antibacterial agent. Glycerol (1:1) may be added for additional stability. Avoid repetitive freeze/thaw cycles.
- Batch Number Please see item label.
- Expiration Date 12 months after date of receipt (unopened vial).
- Alternative Names Voltage-dependent L-type calcium channel subunit beta-2; calcium channel voltage-dependent subunit beta 2; Lambert-Eaton myasthenic syndrome antigen B; MYSB; CACNB2
- Uniprot Number Q08289
- Uniprot Number/Name Q08289 (CACB2_HUMAN)
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Scientific Background
The L-type calcium channel is composed of four subunits: alpha-1, alpha-2, beta and gamma. The beta subunit of voltage-dependent calcium channels aids the function of the calcium channel by increasing the peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting. CAB2 is a membrane protein that is expressed in all tissues. The unprocessed precursor is 660 amino acids in length and has a predicted molecular weight of 74.5KDa. It belongs to the calcium channel beta subunit family and contains one SH3 domain. CAB2 is involved in the MAPK signalling pathway and is also associated with Lambert-Eaton myasthenic syndrome.
- Shipping Temperature 25°C (ambient)
- UNSPSC CODE 41116161
- Regulatory Status For research use only.
