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Ephrin type-B receptor 2, Mouse Monoclonal Antibody
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Catalog Number
M-834
- Product Name Ephrin type-B receptor 2, Mouse Monoclonal Antibody
- Product Description Mouse anti-Ephrin type-B receptor 2 Monoclonal Antibody (Unconjugated), suitable for WB, ELISA.
- Alternative Names Tyrosine-protein kinase receptor EPH-3; DRT; Receptor protein-kinase HEK5; ERK; Tyrosine-protein kinase TYRO5; Renal carcinoma antigen NY-REN-47; EPHB2; DRT; EPHT3; EPTH3; ERK; HEK5; TYRO4
- Application(s) ELISA, WB
- Antibody Host Mouse
- Antibody Type Monoclonal
- Specificity Specificity has been confirmed by WB and direct ELISA against the antigen. This antibody cross reacts with mouse. Other species have not been tested.
- Species Reactivity Human, Mouse
- Immunogen Description Partial recombinant protein of human Ephrin type-B receptor 2 (aa 226 to 325) with a GST tag.
- Conjugate Unconjugated
- Purity Description Protein G purified immunoglobulin
- Regulatory Status For research use only.
Product Info
- Product Description Mouse anti-Ephrin type-B receptor 2 Monoclonal Antibody (Unconjugated), suitable for WB, ELISA.
- Application(s) ELISA, WB
- Application Details This antibody is recommended for WB, and ELISA. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
- Target Ephrin type-B receptor 2
- Specificity Specificity has been confirmed by WB and direct ELISA against the antigen. This antibody cross reacts with mouse. Other species have not been tested.
- Target Host Species Human
- Species Reactivity Human, Mouse
- Antibody Host Mouse
- Antibody Type Monoclonal
- Antibody Isotype IgG
- Clone Name 4D1
- Conjugate Unconjugated
- Immunogen Description Partial recombinant protein of human Ephrin type-B receptor 2 (aa 226 to 325) with a GST tag.
- Purity Description Protein G purified immunoglobulin
- Format Lyophilized from PBS pH 7.2
- Reconstitution Instructions Spin vial briefly before opening. Reconstitute in 100 µL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material.
- Storage Instructions After reconstitution keep aliquots at -20°C for higher stability or at 2-8°C with an appropriate antibacterial agent. Glycerol (1:1) may be added for additional stability. Avoid repetitive freeze/thaw cycles.
- Batch Number Please see item label.
- Expiration Date 12 months after date of receipt (unopened vial).
- Alternative Names Tyrosine-protein kinase receptor EPH-3; DRT; Receptor protein-kinase HEK5; ERK; Tyrosine-protein kinase TYRO5; Renal carcinoma antigen NY-REN-47; EPHB2; DRT; EPHT3; EPTH3; ERK; HEK5; TYRO4
- Uniprot Number P29323
- Uniprot Number/Name P29323 (EPHB2_HUMAN)
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Scientific Background
Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin type-B receptor 2 is a receptor for members of the ephrin-B family and it acts as a tumor suppressor. It is a single-pass type I membrane protein that is expressed in brain, heart, lung, kidney, placenta, pancreas, liver and skeletal muscle. It is preferentially expressedd in fetal brain. Defects in this protein are involved in the development of prostate cancer metastasis to the brain.
- Shipping Temperature 25°C (ambient)
- UNSPSC CODE 41116161
- Regulatory Status For research use only.
